Melatonin is an important endogenous hormone that shows antioxidant functions and
pleiotropic effects, playing a crucial role in animal reproduction. Ovary granulosa cells (GCs) …

Lead (Pb) is a highly toxic heavy metal. Pb exposure could adversely affect many organs,
including the male reproductive system. Oxidative stress and mitochondrial impairment play …

Background Triptolide (TP) is an important active compound from Tripterygium wilfordii Hook
F (Tw HF), however, it is greatly limited in clinical practice due to its severe toxicity …

There is growing concern that chemotherapy drugs can damage Leydig cells and inhibit the
production of testosterone. Increasing evidence shows that melatonin benefits the …

Different aspects of reproductive functions are regulated by mitochondrial-controlled events.
This study investigated the effect of plumbagin (PL) on testicular mitochondria with a view to …

The protective effects of melatonin (Mel) and vitamin E (Vit E) against the negative effects of
acetamiprid (Acmp) on testicles, reproductive hormones, and oxidative stress parameters …

Di‐(2‐ethylhexyl) phthalate (DEHP) is the most widely used plastizer in the world and can
suppress testosterone production via activation of oxidative stress. Genistein (GEN) is one of …

The beneficial effects of quercetin on reproductive damage elicited by 4‐nitrophenol (PNP)
were studied in adult male mice. A six‐week treatment of weekly intraperitoneal injections of …

The present study aims to evaluate the protective effect of grape seed proanthocyanidins
(GSP) on cadmium (Cd)-induced testicular apoptosis, inflammation, and oxidative stress in …

This study aimed to investigate the protective effects of melatonin against arsenic-induced
apoptosis and oxidative stress in rat testes. A total of 27 male rats were divided into 3 …