Multiple lines of evidence suggest that cyclooxygenase‐2 (COX‐2), an inducible form of
COX, represents a potential pharmacologic target to prevent cancer. Key data suggesting a …

Cyclooxygenase-2 (COX-2) is upregulated in a number of epithelial cancers, including in
upper aerodigestive tract (UADT) premalignant and malignant lesions. The purpose of this …

Cyclooxygenase-2 (COX-2) is being intensively evaluated as a pharmacologic target for
both the prevention and treatment of cancer. Aberrant COX-2 expression was initially …

A low incidence of lung carcinoma has been reported in cases of prolonged use of aspirin.
Cyclooxygenase (COX) 2 expression is frequently seen in adenocarcinoma of the lung, but …

The cyclo-oxygenase (COX) metabolic pathway and prostaglandin (PG) production appear
to play a causal role in the promotion and progression of human cancers. COX-1 and COX-2 …

Abstract Cyclooxygenase2 (COX-2), an inducible prostaglandin G/H synthase, is
overexpressed in several human cancers. Here, the potential utility of selective COX-2 …

Abstract Cyclooxygenase‐2 (COX‐2), an enzyme that catalyzes the synthesis of
prostaglandins, is overexpressed in a variety of premalignant and malignant conditions …

We conducted a series of epidemiologic studies to evaluate the chemopreventive effects of
aspirin, ibuprofen, and selective cyxlooxygenase-2 (COX-2) inhibitors (coxibs) against …

COX is the key enzyme in the conversion of arachidonic acid to prostanoids, potent bioactive
lipid derivatives that participate in normal growth responses and in aberrant cellular growth …

Prior to the discovery of cyclooxygenase-2 (COX-2), a beneficial association was shown
between chronic usage of non steroidal anti-inflammatory drugs (NSAIDs), that …