The prevalence and risk factors for gallstone disease

EH Yoo, SY Lee - Clinical chemistry and laboratory medicine, 2009 - degruyter.com
Gallstone disease is one of the most prevalent gastrointestinal disorders. In addition, the
costs associated with the diagnosis and treatment of gallstone disease have been rapidly …

Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China

G Andreotti, J Chen, YT Gao, A Rashid, BE Chen… - … Biomarkers & Prevention, 2008 - AACR
Biliary tract cancers, encompassing the gallbladder, extrahepatic bile duct, and ampulla of
Vater, are uncommon yet highly fatal malignancies. Gallstones, the primary risk factor for …

Relationship between CYP7A1 -204A > C polymorphism with gallbladder stone disease and serum lipid levels: a meta-analysis

Q Cai, ZQ Wang, Q Cai, C Li, EZ Chen… - Lipids in health and …, 2014 - Springer
Abstract Background The CYP7A1 gene polymorphism has been reported to be associated
with gallbladder stone disease (GSD) and serum lipid levels, but the results were …

Significant role of estrogen and progesterone receptor sequence variants in gallbladder cancer predisposition: a multi-analytical strategy

A Srivastava, KL Sharma, N Srivastava, S Misra… - PLoS …, 2012 - journals.plos.org
Background Carcinoma of gallbladder (GBC) is an aggressive malignancy. The higher
incidence of gallbladder cancer in women has been partly attributed to hormonal factors …

The Amerindian's genes in the Mexican population are associated with development of gallstone disease

N Méndez-Sánchez, AC King-Martínez… - Official journal of the …, 2004 - journals.lww.com
BACKGROUND: It has been suggested that genes related to Amerindian ancestry account
for the high prevalence of gallstone disease (GD) observed in Mexican-Americans. The HLA …

The genetics of primary biliary cholangitis: a GWAS and post-GWAS update

Y Hitomi, M Nakamura - Genes, 2023 - mdpi.com
Primary biliary cholangitis (PBC) is a chronic, progressive cholestatic liver disease in which
the small intrahepatic bile ducts are destroyed by autoimmune reactions. Among …

Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone disease

I Rudkowska, PJH Jones - Nutrition reviews, 2008 - academic.oup.com
ATP-binding cassette (ABC) transporters function in the homeostasis of lipids. Dysfunction of
ABC transporters is frequently associated with disease. This review examines links between …

[HTML][HTML] Polymorphisms at cholesterol 7α-hydroxylase, apolipoproteins B and E and low density lipoprotein receptor genes in patients with gallbladder stone disease

ZY Jiang, TQ Han, GJ Suo, DX Feng… - World Journal of …, 2004 - ncbi.nlm.nih.gov
AIM: To investigate the relationship between gallbladder stone disease (GSD) and single
nucleotide polymorphisms of cholesterol 7α-hydroxylase (CYP7A) gene promoter …

Significantly increased risk of cardiovascular disease among patients with gallstone disease: a population-based cohort study

MT Olaiya, HY Chiou, JS Jeng, LM Lien, FI Hsieh - PloS one, 2013 - journals.plos.org
Objective To investigate whether gallstone disease (GD) increases the risk of developing
cardiovascular disease (CVD) in a large population-based cohort. Methods A study …

The relation between gallstone disease and cardiovascular disease

LL Fan, BH Chen, ZJ Dai - Scientific reports, 2017 - nature.com
Gallstone disease (GD) is a common digestive disorder that shares many risk factors with
cardiovascular disease (CVD). CVD is an important public health issue that encompasses a …