[HTML][HTML] EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells

T Yokoyama, J Tam, S Kuroda, AW Scott, J Aaron… - PloS one, 2011 - journals.plos.org
Background The epidermal growth factor receptor (EGFR) is overexpressed in 80% of non-
small cell lung cancer (NSCLC) and is associated with poor survival. In recent years, EGFR …

EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage

S Kuroda, J Tam, JA Roth, K Sokolov… - International journal of …, 2014 - Taylor & Francis
Background We have previously demonstrated the epidermal growth factor receptor (EGFR)-
targeted hybrid plasmonic magnetic nanoparticles (225-NP) produce a therapeutic effect in …

[HTML][HTML] Novel nanoparticle-based cancer treatment, effectively inhibits lung metastases and improves survival in a murine breast cancer model

S Kraus, R Khandadash, R Hof, A Nyska… - Frontiers in …, 2021 - frontiersin.org
Sarah Nanoparticles (SaNPs) are unique multicore iron oxide-based nanoparticles,
developed for the treatment of advanced cancer, following standard care, through the …

Assessing the selective therapeutic efficacy of superparamagnetic erlotinib nanoparticles in lung cancer by using quantitative magnetic resonance imaging and a …

FT Hsu, HS Liu, AAA Ali, PH Tsai, YC Kao… - … , Biology and Medicine, 2018 - Elsevier
Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer. Epidermal
growth factor receptor (EGFR) tyrosine kinase inhibitors are commonly used as the first-line …

[HTML][HTML] Low frequency magnetic fields induce autophagy-associated cell death in lung cancer through miR-486-mediated inhibition of Akt/mTOR signaling pathway

Y Xu, Y Wang, A Yao, Z Xu, H Dou, S Shen, Y Hou… - Scientific reports, 2017 - nature.com
Low frequency magnetic fields (LF-MFs) can affect cell proliferation in a cell-type and
intensity-dependent way. Previous study has reported the anti-tumor effect of LF-MFs in lung …

Anti-HER2 antibody and ScFvEGFR-conjugated antifouling magnetic iron oxide nanoparticles for targeting and magnetic resonance imaging of breast cancer

H Chen, L Wang, Q Yu, W Qian, D Tiwari… - International journal …, 2013 - Taylor & Francis
Antifouling magnetic iron oxide nanoparticles (IONPs) coated with block copolymer poly
(ethylene oxide)-block-poly (γ-methacryloxypropyltrimethoxysilane)(PEO-b-PγMPS) were …

Apoptosis-promoting effect of rituximab-conjugated magnetic nanoprobes on malignant lymphoma cells with CD20 overexpression

L Song, W Zhang, H Chen, X Zhang, H Wu… - International journal …, 2019 - Taylor & Francis
Background Cancer targeting nanoprobes with precisely designed physicochemical
properties may show enhanced pharmacological targeting and therapeutic efficacy. As a …

[HTML][HTML] Enhanced anti-tumor of pep-1 modified superparamagnetic iron oxide/PTX loaded polymer nanoparticles

B Wang, W Wu, H Lu, Z Wang, H Xin - Frontiers in pharmacology, 2019 - frontiersin.org
Superparamagnetic iron-oxide nanoparticle (SPION) has gained tremendous attention for
drug delivery applications due to their unique properties. In this study, we developed a dual …

A review on engineered magnetic nanoparticles in Non-Small-Cell lung carcinoma targeted therapy

LM Ngema, SA Adeyemi, T Marimuthu… - International Journal of …, 2021 - Elsevier
There are growing appeals for the design of efficacious treatment options for non-small-cell
lung carcinoma (NSCLC) as it accrues to~ 85% cases of lung cancer. Although platinum …

[HTML][HTML] Anti‑CD206 antibody‑conjugated Fe3O4‑based PLGA nanoparticles selectively promote tumor‑associated macrophages to polarize to the pro‑inflammatory …

Y Zhou, KT Que, HM Tang, P Zhang… - Oncology …, 2020 - spandidos-publications.com
M2 macrophages serve roles in inhibiting inflammation and promoting tumor development.
Reversing tumor‑associated macrophages (TAMs) from M2‑to M1‑type polarization may …