Great efforts are being made worldwide to identify the specific clinical characteristics of
infected critically ill patients that mediate the associated pathogenesis, including vascular …

Objectives: The causative agent for coronavirus disease 2019, severe acute respiratory
syndrome coronavirus 2, appears exceptional in its virulence and immunopathology. In …

Objective: Coronavirus disease 2019 is a heterogeneous disease most frequently causing
respiratory tract infection, which can induce respiratory failure and multiple organ …

Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to
infection. Sepsis is a global burden killing~ 11 million persons annually. In December 2019 …

OBJECTIVES: To identify research priorities in the management, pathophysiology, and host
response of coronavirus disease 2019 in critically ill patients. DESIGN: The Surviving Sepsis …

Objectives: Coronavirus disease 2019 is caused by severe acute respiratory syndrome-
coronavirus-2 infection to which there is no community immunity. Patients admitted to ICUs …

Abstract Background Until June 23th 2020, 9,195,635 laboratory-confirmed cases of Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection have been reported …

Current management guidelines for COVID-19 reflect the assumption that critically ill
patients infected with SARS-CoV-2 develop acute respiratory distress syndrome (ARDS) …

Background The infection caused by SARS CoV-2 has been postulated to induce a cytokine
storm syndrome that results in organ failure and even death in a considerable number of …

Objectives: Recent studies have reported a high prevalence of thrombotic events in
coronavirus disease 2019. However, the significance of thromboembolic complications has …