Recent progress in detection and profiling of cancer cell‐derived exosomes

H Xiong, Z Huang, Z Yang, Q Lin, B Yang, X Fang… - Small, 2021 - Wiley Online Library
Exosomes, known as nanometer‐sized vesicles (30–200 nm), are secreted by many types of
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …

Absolute quantification of serum exosomes in patients with an sers-lateral flow strip biosensor for noninvasive clinical cancer diagnosis

X Su, Y Xie, X Liu, M Chen, C Zheng… - ACS Applied Materials …, 2023 - ACS Publications
Exosomes (exos) widely existing in body fluids show great potential for noninvasive cancer
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …

Designed Co-DNA-locker and ratiometric SERS sensing for accurate detection of exosomes based on gold nanorod arrays

J Wang, H Xie, C Ding - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Exosomes, which can transfer and deliver information about the original cell, are considered
to be ideal candidates for early cancer diagnosis and evaluation of therapeutic efficacy due …

Highly Sensitive Exosome Detection for Early Diagnosis of Pancreatic Cancer Using Immunoassay Based on Hierarchical Surface‐Enhanced Raman Scattering …

J Li, Y Li, S Chen, W Duan, X Kong, Y Wang… - Small …, 2022 - Wiley Online Library
Exosomes have emerged as potential biomarkers for pancreatic cancer (PaC). However, it is
still challenging to get quantitative detection of exosomes with the specific surface receptors …

Bimetallic nanoplasmonic gap-mode SERS substrate for lung normal and cancer-derived exosomes detection

K Sivashanmugan, WL Huang, CH Lin, JD Liao… - Journal of the Taiwan …, 2017 - Elsevier
Surface-enhanced Raman scattering (SERS) has received significant attention for analytical
and diagnostic applications in cancer research due to its potency for detecting low …

Multifunctional detection of extracellular vesicles with surface plasmon resonance microscopy

Y Yang, C Zhai, Q Zeng, AL Khan, H Yu - Analytical Chemistry, 2020 - ACS Publications
Extracellular vesicles (EVs), including exosomes, are promising circulating biomarkers for
disease diagnosis. Conventional EVs analysis requires multiple instrumentations to obtain …

Construction of exosome SORL1 detection platform based on 3D porous microfluidic chip and its application in early diagnosis of colorectal cancer

P Li, J Chen, Y Chen, S Song, X Huang, Y Yang, Y Li… - Small, 2023 - Wiley Online Library
Exosomes are promising new biomarkers for colorectal cancer (CRC) diagnosis, due to their
rich biological fingerprints and high level of stability. However, the accurate detection of …

Localized plasmonic sensor for direct identifying lung and colon cancer from the blood

C Lin, S Liang, Y Li, Y Peng, Z Huang, Z Li… - Biosensors and …, 2022 - Elsevier
The tissue inhibitor of metalloproteinases-1 (TIMP-1) protein can regulate the expression of
certain proteases and microRNAs in cancer cells, and it is highly possible to diagnose …

Ultrasensitive Detection of Exosomes Using an Optical Microfiber Decorated with Plasmonic MoSe2-Supported Gold Nanorod Nanointerfaces

H Li, T Huang, L Lu, H Yuan, L Zhang, H Wang… - ACS …, 2022 - ACS Publications
Exosomes are potential and promising natural noninvasive biomarkers for liquid biopsies
and can be involved in various biological and pathological processes in early-stage cancer …

Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping

X Su, X Liu, Y Xie, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …