A Novel Catalase Nanogels for Effective Treatment of Neutrophilic Asthma

X Zuo, X Guo, Y Gu, D Zhao, Z Zou… - Advanced Functional …, 2024 - Wiley Online Library
Neutrophilic asthma, as corticosteroid resistant asthma, is clinically more severe than
eosinophilic asthma. Therefore, the treatment of neutrophilic asthma has been a …

Mucoadhesive, antibacterial, and reductive nanogels as a mucolytic agent for efficient nebulized therapy to combat allergic asthma

D Zhao, D Li, X Cheng, Z Zou, X Chen, C He - ACS nano, 2022 - ACS Publications
Asthma is an intractable disease involving the infiltration of inflammatory cells and mucus
plugging. Despite small molecular mucolytics having the ability to break the disulfide bonds …

An antibacterial, multifunctional nanogel for efficient treatment of neutrophilic asthma

X Zuo, X Guo, D Zhao, Y Gu, Z Zou, Y Shen… - Journal of Controlled …, 2024 - Elsevier
Asthma is a chronic and heterogeneous disease affecting the lungs and respiratory tract. In
particular, the neutrophil subtype of asthma was described as persistent, more severe, and …

[HTML][HTML] A bio-adhesion nanogel particle as an anti-inflammation agent for efficient aerosol inhalation therapy to asthma

YB Chen, JY Hou, XY Yue, YQ Wang, J Huang, D Xu… - Materials & Design, 2024 - Elsevier
Asthma is a heterogeneous respiratory disease characterized by airway inflammation
occurring in the bronchus. Direct delivery of targeted treatments to the bronchus for asthma …

Site-specific inhibition of neutrophilic inflammation by low-dose nanotherapy for immunoregulatory treatment of asthma

L Li, Y Ma, Y Hu, P Wang, S Han, X Zhang, J Zhang - Nano Today, 2023 - Elsevier
Asthma, one of the most common lung diseases, remains a serious global health problem.
Currently there is still an urgent need for effective and safe therapies against severe asthma …

[HTML][HTML] Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells

J Cai, H Tao, H Liu, Y Hu, S Han, W Pu, L Li, G Li, C Li… - Bioactive Materials, 2023 - Elsevier
Asthma is a serious global public health concern. Airway neutrophilic inflammation is closely
related to severe asthma, for which effective and safe therapies remain to be developed …

Catalase nanocapsules protected by polymer shells for scavenging free radicals of tobacco smoke

L Liu, W Yu, D Luo, Z Xue, X Qin, X Sun… - Advanced Functional …, 2015 - Wiley Online Library
Free radicals in tobacco smoke trigger numerous lung diseases, which are worldwide health
considerations. The ideal free‐radical, tobacco‐smoke scavenger must be highly reactive …

A novel inhalable quercetin-alginate nanogel as a promising therapy for acute lung injury

YB Chen, YB Zhang, YL Wang, P Kaur… - Journal of …, 2022 - Springer
Background Acute lung injury (ALI), a severe health-threatening disease, has a risk of
causing chronic pulmonary fibrosis. Informative and powerful evidence suggests that …

In situ derived sulfated/sulfonated carbon nanogels with multi-protective effects against influenza a virus

HY Lin, KL Luo, JY Mao, CJ Lin, CY Wang… - Chemical Engineering …, 2023 - Elsevier
Pandemic of H1N1 infections are frequently reported around the world. Despite the
availability of influenza remedies, the high tendency for influenza virus to mutate can lead to …

Chitosan-centered nanosystems as sustained therapeutics for allergic rhinitis intervention: inhibition of histamine-induced cascades

M Sun, D Qin, P Fan, X Chen, Y Liu - Journal of Controlled Release, 2021 - Elsevier
Abstract Allergic rhinitis (AR), histamine-mediated upper airway inflammatory disorder, is
characterized by sneezing, itching, airway hyperreactivity, etc. Though it is clinically well …