Akt, or protein kinase B, is a multifunctional serine-threonine protein kinase implicated in a
diverse range of cellular functions including cell metabolism, survival, migration, and gene …

Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as
migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the …

Akt is a serine/threonine protein kinase that is activated by a number of growth factors and
cytokines in a phosphatidylinositol-3 kinase–dependent manner. Although antiapoptotic …

The PI3K/Akt pathway is necessary for several key endothelial cell (EC) functions, including
cell growth, migration, survival, and vascular tone. However, existing literature supports the …

Akt kinases control essential cellular functions, including proliferation, apoptosis,
metabolism and transcription, and have been proposed as promising targets for treatment of …

The mammalian serine/threonine Akt kinases comprise three closely related isoforms: Akt1,
Akt2 and Akt3. Akt activation has been implicated in both normal and disease processes …

The serine/threonine kinase Akt, also known as protein kinase B (PKB), is a central node in
cell signaling downstream of growth factors, cytokines, and other cellular stimuli. Aberrant …

The serine/threonine kinase Akt, also named protein kinase B, plays a central role in
promoting the survival of a wide range of cell types. 1 In this issue of Circulation Research …

Protein kinase B (Akt1) holds a central role for cellular growth, development, and survival,
but the cellular pathways of Akt1 that prevent inflammatory demise in the vascular system …

Akt is an important signaling molecule that modulates many cellular processes such as cell
growth, survival, and metabolism. Akt activation has been proposed as a potential strategy …