Neuroprotection trials in traumatic brain injury
S Chakraborty, B Skolnick, RK Narayan - Current neurology and …, 2016 - Springer
Traumatic brain injury (TBI) is a significant cause of mortality and morbidity worldwide.
Current treatment of acute TBI includes surgical intervention when needed, followed by …
Current treatment of acute TBI includes surgical intervention when needed, followed by …
Neuroprotection for traumatic brain injury
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Despite
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
A review of neuroprotection pharmacology and therapies in patients with acute traumatic brain injury
Traumatic brain injury (TBI) affects 1.6 million Americans annually. The injury severity
impacts the overall outcome and likelihood for survival. Current treatment of acute TBI …
impacts the overall outcome and likelihood for survival. Current treatment of acute TBI …
Emerging treatments for traumatic brain injury
Y Xiong, A Mahmood, M Chopp - Expert opinion on emerging drugs, 2009 - Taylor & Francis
Background: This review summarizes promising approaches for the treatment of traumatic
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …
Critical appraisal of neuroprotection trials in head injury: what have we learned?
CM Tolias, MR Bullock - NeuroRx, 2004 - Springer
To date, despite very encouraging preclinical results, almost all phase II/III clinical
neuroprotection trials in traumatic brain injury (TBI) have failed to show any consistent …
neuroprotection trials in traumatic brain injury (TBI) have failed to show any consistent …
Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury
MI Hiskens - Journal of Pharmacology and Experimental …, 2022 - ASPET
Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …
manifests in cognitive, behavioral, and motor impairment. Although there have been …
Recent developments in clinical trials for the treatment of traumatic brain injury
DG Stein, RI Geddes, EA Sribnick - Handbook of clinical neurology, 2015 - Elsevier
The clinical understanding of traumatic brain injury (TBI) and its manifestations is beginning
to change. Both clinicians and research scientists are recognizing that TBI and related …
to change. Both clinicians and research scientists are recognizing that TBI and related …
Neuroprotective agents in traumatic brain injury
AIR Maas - Expert opinion on investigational drugs, 2001 - Taylor & Francis
The role of neuroprotection in traumatic brain injury (TBI) is reviewed. Basic research and
experimental investigations have identified many different compounds with potential …
experimental investigations have identified many different compounds with potential …
Design of acute neuroprotection studies
GWJ Hawryluk, MR Bullock - Handbook of clinical neurology, 2015 - Elsevier
Traumatic brain injury (TBI) is a substantial public health problem. The discovery of
progressive, ongoing damage to the brain by means of complex molecular mechanisms …
progressive, ongoing damage to the brain by means of complex molecular mechanisms …
Neuroprotection in traumatic brain injury.
Traumatic brain injury (TBI) has a high incidence worldwide and is associated with
significant morbidity and mortality. TBI has enduring implications in several domains and …
significant morbidity and mortality. TBI has enduring implications in several domains and …