Transposable elements possess specific patterns of integration. The biological impact of
these integration profiles is not well understood. Tf1, a long-terminal repeat retrotransposon …

Transposable elements (TEs) constitute a substantial fraction of the eukaryotic genome and,
as a result, have a complex relationship with their host that is both adversarial and …

The biological impact of transposons on the physiology of the host depends greatly on the
frequency and position of integration. Previous studies of Tf1, a long terminal repeat …

The successful dispersal of transposons depends on the critical balance between the fitness
of the host and the ability of the transposon to insert into the host genome. One method …

Target site selection of transposable elements is usually not random but involves some
specificity for a DNA sequence or a DNA binding host factor. We have investigated the target …

Background: Heat-shock proteins (hsps) are thought to protect cells against stresses,
especially due to elevated temperatures. But while genetic manipulation of hsp gene …

The LTR-retrotransposon Tf1 preserves the coding capacity of its host
Schizosaccharomyces pombe by integrating upstream of open reading frames (ORFs). To …

The Ty1 long terminal repeat (LTR) retrotransposon of Saccharomyces cerevisiae is a
powerful model to understand the activation of transposable elements by stress and their …

A relationship between transposable elements (TEs) and the eukaryotic stress response
was suggested in the first publications describing TEs. Since then, it has often been …

Cells are regularly exposed to a range of naturally occurring stress that can restrict growth or
cause lethality. In response, cells activate expression networks with hundreds of genes that …