Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
RJ Docherty, JC Yeats, S Bevan, H Boddeke - Pflügers Archiv, 1996 - Springer
Capsaicin activates a non-specific cation conductance in mammalian sensory neurones. If
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
A study of the voltage dependence of capsaicin‐activated membrane currents in rat sensory neurones before and after acute desensitization
AS Piper, JC Yeats, S Bevan… - The Journal of …, 1999 - Wiley Online Library
1 Responses to capsaicin in isolated sensory neurones have been shown to desensitize in
a Ca2+‐and voltage‐dependent manner. We have studied desensitization of capsaicin …
a Ca2+‐and voltage‐dependent manner. We have studied desensitization of capsaicin …
The role of calcium in capsaicin-induced desensitization in rat cultured dorsal root ganglion neurons
A Cholewinski, GM Burgess, S Bevan - Neuroscience, 1993 - Elsevier
The effects of capsaicin cytosolic Ca 2+ concentration ([Ca 2+] i) were measured in
individual dorsal root ganglion neurons of the rat in culture. Capsaicin produced a rapid …
individual dorsal root ganglion neurons of the rat in culture. Capsaicin produced a rapid …
Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult rat dorsal root ganglion neurons in culture
RJ Docherty, B Robertson, S Bevan - Neuroscience, 1991 - Elsevier
The effect of capsaicin on voltage-activated calcium currents was investigated in
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons
PA Koplas, RL Rosenberg, GS Oxford - Journal of Neuroscience, 1997 - Soc Neuroscience
Capsaicin (Cap) is a pungent extract of the Capsicum pepper family, which activates
nociceptive primary sensory neurons. Inward current and membrane potential responses of …
nociceptive primary sensory neurons. Inward current and membrane potential responses of …
The effect of capsaicin on voltage‐gated calcium currents and calcium signals in cultured dorsal root ganglion cells
D Bleakman, JR Brorson… - British journal of …, 1990 - Wiley Online Library
1 The effects of capsaicin on voltage‐gated Ca2+ currents (ICa), and intracellular Ca2+
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro
SJ Marsh, CE Stansfeld, DA Brown, R Davey… - Neuroscience, 1987 - Elsevier
The selective excitant and neurotoxic action of capsaicin on vagal sensory neurons in the rat
has been investigated in vitro using three techniques: extracellular recording of compound …
has been investigated in vitro using three techniques: extracellular recording of compound …
Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture
RJ Docherty, JC Yeats, AS Piper - British journal of pharmacology, 1997 - ncbi.nlm.nih.gov
Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion
neurones in culture Page 1 Capsazepine block of voltage-activated calcium channels in adult …
neurones in culture Page 1 Capsazepine block of voltage-activated calcium channels in adult …
Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons
Capsaicin (CAP), a neurotoxin, has been reported to activate a nonselective cation current
in dorsal root ganglion (DRG) neurons. In this paper, we identify and describe the properties …
in dorsal root ganglion (DRG) neurons. In this paper, we identify and describe the properties …
Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells
M Petersen, RH LaMotte - Pain, 1993 - Elsevier
Capsaicin excites a subset of dorsal root ganglion (DRG) neurons by inducing an inward
current. We have examined this inward current in response to high concentrations of protons …
current. We have examined this inward current in response to high concentrations of protons …