[HTML][HTML] Type 2 diabetes is associated with loss of HDL endothelium protective functions
T Vaisar, E Couzens, A Hwang, M Russell, CE Barlow… - PLoS …, 2018 - journals.plos.org
Aims/Hypothesis One of the hallmarks of diabetes is impaired endothelial function. Previous
studies showed that HDL can exert protective effects on endothelium stimulating NO …
studies showed that HDL can exert protective effects on endothelium stimulating NO …
[HTML][HTML] The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
Background Functional properties of high density lipoproteins (HDL) are increasingly
recognized to play a physiological role in atheroprotection. Type 2 diabetes mellitus (T2DM) …
recognized to play a physiological role in atheroprotection. Type 2 diabetes mellitus (T2DM) …
Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin …
SA Sorrentino, C Besler, L Rohrer, M Meyer… - Circulation, 2010 - Am Heart Assoc
Background—High-density lipoprotein (HDL)–raising therapies are currently under intense
evaluation, but the effects of HDL may be highly heterogeneous. We therefore compared the …
evaluation, but the effects of HDL may be highly heterogeneous. We therefore compared the …
Dysfunctional HDL in diabetes mellitus and its role in the pathogenesis of cardiovascular disease
RAK Srivastava - Molecular and cellular biochemistry, 2018 - Springer
Coronary artery disease, the leading cause of death in the developed and developing
countries, is prevalent in diabetes mellitus with 68% cardiovascular disease (CVD)-related …
countries, is prevalent in diabetes mellitus with 68% cardiovascular disease (CVD)-related …
HDL functionality in type 1 diabetes
S Ganjali, GM Dallinga-Thie, LE Simental-Mendía… - Atherosclerosis, 2017 - Elsevier
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by absence
of insulin secretion due to destruction of the pancreatic beta-cells. Patients with T1D exhibit …
of insulin secretion due to destruction of the pancreatic beta-cells. Patients with T1D exhibit …
[HTML][HTML] HDL particle size is increased and HDL-cholesterol efflux is enhanced in type 1 diabetes: a cross-sectional study
MO Ahmed, RE Byrne, A Pazderska, R Segurado… - Diabetologia, 2021 - Springer
Aims/hypothesis The prevalence of atherosclerosis is increased in type 1 diabetes despite
normal-to-high HDL-cholesterol levels. The cholesterol efflux capacity (CEC) of HDL is a …
normal-to-high HDL-cholesterol levels. The cholesterol efflux capacity (CEC) of HDL is a …
The anti-inflammatory function of high-density lipoprotein in type II diabetes: A systematic review
RFH Lemmers, M van Hoek, AG Lieverse… - Journal of clinical …, 2017 - Elsevier
Background Inflammation is a pathophysiological factor in diabetes and its cardiovascular
complications. High-density lipoprotein (HDL) suppresses inflammation in healthy …
complications. High-density lipoprotein (HDL) suppresses inflammation in healthy …
[HTML][HTML] The endothelium is both a target and a barrier of HDL's protective functions
The vascular endothelium serves as a barrier between the intravascular and extravascular
compartments. High-density lipoproteins (HDL) have two kinds of interactions with this …
compartments. High-density lipoproteins (HDL) have two kinds of interactions with this …
Normal HDL cholesterol efflux and anti-inflammatory capacities in type 2 diabetes despite lipidomic abnormalities
D Denimal, S Benanaya, S Monier… - The Journal of …, 2022 - academic.oup.com
Objective To assess whether, in type 2 diabetes (T2D) patients, lipidomic abnormalities in
high-density lipoprotein (HDL) are associated with impaired cholesterol efflux capacity and …
high-density lipoprotein (HDL) are associated with impaired cholesterol efflux capacity and …
High-density lipoproteins rescue diabetes-impaired angiogenesis via scavenger receptor class B type I
JTM Tan, HCG Prosser, LL Dunn, LZ Vanags… - Diabetes, 2016 - Am Diabetes Assoc
Disordered neovascularization and impaired wound healing are important contributors to
diabetic vascular complications. We recently showed that high-density lipoproteins (HDLs) …
diabetic vascular complications. We recently showed that high-density lipoproteins (HDLs) …