Experimental autoimmune neuritis (EAN) is a widely used animal model of the human acute
inflammatory demyelinating polyradiculoneuropathy, which is the most common subtype of …

Abstract Guillain–Barre'syndrome (GBS) is an acute, postinfectious, immune-mediated,
demyelinating disease of peripheral nerves and nerve roots. As a classical animal model of …

Objective In this study, we studied whether minocycline hydrochloride improved neuropathic
pain induced by spinal cord injury (SCI) in rats through PI3K/Akt pathway. Methods The SCI …

We investigated the anti-inflammatory effects of minocycline in EAE, an animal model of MS.
Minocycline, administered for two weeks after the clinical onset, significantly decreased the …

Guillain–Barré syndrome (GBS) is an acute inflammatory and immune-mediated
demyelinating disease of the peripheral nervous system (PNS). Macrophages play a central …

Objective Minocycline, a second-generation tetracycline-class antibiotic, has been well
established to exert a neuroprotective effect in animal models and neurodegenerative …

Spinal cord injury (SCI) is known as a debilitating condition which usually occurs due to
traumas to the spine. However, the injury could also occur during clinical interventions such …

Substantial evidence indicates involvement of microglia/macrophages in chronic
neuropathic pain. However, the temporal-spatial features of microglial/macrophage …

Experimental autoimmune neuritis (EAN) is a T cell-mediated autoimmune inflammatory
demyelinating disease of the peripheral nervous system and widely-used animal model of …

Previous evidence demonstrated that minocycline could ameliorate clinical severity of
experimental autoimmune encephalomyelitis and exhibit several anti-inflammatory and …