The role of the serotonin receptor subtypes 5-HT1A and 5-HT7 and its interaction in emotional learning and memory

O Stiedl, E Pappa, Å Konradsson-Geuken… - Frontiers in …, 2015 - frontiersin.org
Serotonin [5-hydroxytryptamine (5-HT)] is a multifunctional neurotransmitter innervating
cortical and limbic areas involved in cognition and emotional regulation. Dysregulation of …

5-HT1A and 5-HT7 receptor crosstalk in the regulation of emotional memory: implications for effects of selective serotonin reuptake inhibitors

TM Eriksson, S Holst, TL Stan, T Hager, B Sjögren… - …, 2012 - Elsevier
This study utilized pharmacological manipulations to analyze the role of direct and indirect
activation of 5-HT7 receptors (5-HT7Rs) in passive avoidance learning by assessing …

Serotonin receptor 4 in the hippocampus modulates mood and anxiety

R Karayol, L Medrihan, JL Warner-Schmidt… - Molecular …, 2021 - nature.com
Abstract Serotonin receptor 4 (5-HT4R) plays an important role in regulating mood, anxiety,
and cognition, and drugs that activate this receptor have fast-acting antidepressant (AD)-like …

The role of serotonin 5-HT2A receptors in memory and cognition

G Zhang, RW Stackman Jr - Frontiers in pharmacology, 2015 - frontiersin.org
Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …

The role of 5-HT1A receptors in learning and memory

SO Ögren, TM Eriksson, E Elvander-Tottie… - Behavioural brain …, 2008 - Elsevier
The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus,
septum and amygdala, all representing brain regions associated with various domains of …

Interplay between Serotonin 5‐HT1A and 5‐HT7 Receptors in Depressive Disorders

VS Naumenko, NK Popova, E Lacivita… - CNS neuroscience & …, 2014 - Wiley Online Library
Summary Serotonin (5‐hydroxytryptamine or 5‐HT) is an important neurotransmitter
regulating a wide range of physiological and pathological functions via activation of …

Serotonin and emotion, learning and memory

A Meneses, G Liy-Salmeron - Reviews in the Neurosciences, 2012 - degruyter.com
Abstract Serotonin (5-hydroxytryptamien, 5-HT) has been linked to emotional and
motivational aspects of human behavior, including anxiety, depression, impulsivity, etc …

A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory

MV King, CA Marsden, KCF Fone - Trends in pharmacological sciences, 2008 - cell.com
The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …

Serotonin 1A and serotonin 4 receptors: essential mediators of the neurogenic and behavioral actions of antidepressants

BA Samuels, I Mendez-David, C Faye… - The …, 2016 - journals.sagepub.com
Selective serotonin reuptake inhibitors are the mostly widely used treatment for major
depressive disorders and also are prescribed for several anxiety disorders. However, similar …

5-HT7 receptor stimulation and blockade: a therapeutic paradox about memory formation and amnesia

A Meneses - Frontiers in behavioral neuroscience, 2014 - frontiersin.org
Mammalian memory involves multiple brain areas and neurotransmitter systems; both at the
receptor and post-receptor level (Meneses, 2014a, b). Investigations of serotonin (5 …