BACKGROUND This study presents a comprehensive survey and characterization of
available prostate carcinoma cell lines, most of which have been widely used but are …

PURPOSE:: This is part 2 of a 2-part review. Research into the molecular mechanisms
underlying the various aspects of prostate cancer (PCa) requires the use of in vivo and in …

PURPOSE:: This is part 1 of a 2-part review. Research into the molecular mechanisms
underlying the various aspects of prostate cancer (PCa) requires the use of in vivo and in …

HE MOLECULAR biology of human cancer has seen explosive progress in the last decade.
This progress has been the result of both technical and conceptual advances, reinforcing …

BACKGROUND The study of prostate carcinogenesis and tumor progression is made
difficult by the lack of appropriate in vitro and in vivo models. High prevalence of prostatic …

Prostate cancer is a biologically heterogeneous disease with considerable variation in
clinical aggressiveness. The behavior of prostate cancer can be considered a direct or …

BACKGROUND Cross‐contamination is a persistent problem in the establishment and
maintenance of mammalian cell lines. The observation that the cell lines PC‐3, ALVA‐31 …

In spite of progress in diagnosis and treatment, prostate cancer has become one of the most
frequent lethal cancers in males in many Western industrialized countries. Research on the …

Background Prostate cancer is a broad-spectrum disease, spanning from indolent to a
highly aggressive lethal malignancy. Prostate cancer cell lines are essential tools to …

BACKGROUND Almost all attempts at establishing prostate carcinoma cell lines have
resulted in generation of cells that are androgen‐independent, including commonly used …