Outcomes of patients with acute severe autoimmune hepatitis: Predictors of non‐response to corticosteroids and need for liver transplantation

A Eshraghian, A Taghavi… - United European …, 2024 - Wiley Online Library
Abstract Background and Aims Acute severe autoimmune hepatitis (AS‐AIH) is an evolving
concept and the outcomes and optimal treatment have been less studied. In this study, we …

Prognosis of acute severe autoimmune hepatitis (AS-AIH): the role of corticosteroids in modifying outcome

AD Yeoman, RH Westbrook, Y Zen, W Bernal… - Journal of …, 2014 - Elsevier
Background & Aims No standardised definition exists for acute, severe AIH (AS-AIH).
However, rapid identification of AS-AIH and early corticosteroid therapy may prevent the …

Early predictors of corticosteroid response in acute severe autoimmune hepatitis: a nationwide multicenter study

L Téllez, E Sánchez Rodríguez… - Alimentary …, 2022 - Wiley Online Library
Summary Background and Aims To assess whether corticosteroids improve prognosis in
patients with AS‐AIH, and to identify factors at therapy initiation and during therapy …

[HTML][HTML] Clinical characteristics and treatment outcomes of acute severe autoimmune hepatitis

L Zheng, Y Liu, Y Shang, Z Han, Y Han - BMC gastroenterology, 2021 - Springer
Background and aim Acute severe autoimmune hepatitis (AS-AIH) is a rare cause of acute
liver failure (ALF), which is often neglected and delayed in treatment. The purpose of this …

Prompt initiation of high‐dose iv corticosteroids seems to prevent progression to liver failure in patients with original acute severe autoimmune hepatitis

K Zachou, P Arvaniti, K Azariadis… - Hepatology …, 2019 - Wiley Online Library
Aims The definition of original acute severe autoimmune hepatitis (AS‐AIH) is unclear.
However, its rapid recognition and early treatment is potentially life‐saving. Therefore, we …

Natural history and treatment outcomes of severe autoimmune hepatitis

N Sonthalia, PM Rathi, SS Jain… - Journal of Clinical …, 2017 - journals.lww.com
Background: Severe acute presentation is an uncommon manifestation of AIH, and it
remains poorly characterized. Materials and Methods: We included 101 patients with AIH …

Acute severe autoimmune hepatitis: corticosteroids or liver transplantation?

GN Dalekos, NK Gatselis, K Zachou - Liver Transplantation, 2019 - journals.lww.com
We read with interest the review by Rahim et al.,(1) in which they gave an elegant summary
of the role, predictors, and optimal timing of corticosteroids and liver transplantation (LT) in …

[HTML][HTML] Approach to the patient with acute severe autoimmune hepatitis

MN Rahim, R Miquel, MA Heneghan - JHEP Reports, 2020 - Elsevier
Autoimmune hepatitis is associated with varied clinical presentations and natural history, as
well as somewhat unpredictable treatment responses. Understanding how to stratify patients …

Reply to “The role of corticosteroids in acute-severe autoimmune hepatitis is still highly debatable”

AD Yeoman, S Kotha… - Journal of Hepatology, 2015 - journal-of-hepatology.eu
We thank Dr. de Martin and colleagues for their interest in our paper ''Acute-severe
autoimmune hepatitis (AS-AIH): The role of corticosteroids in improving outcome''. We …

[PDF][PDF] Acute severe autoimmune hepatitis: corticosteroids or liver transplantation?

MN Rahim, R Liberal, R Miquel, ND Heaton… - Liver …, 2019 - Wiley Online Library
Acute severe presentations of autoimmune hepatitis (AIH) represent a challenge for the
transplant community. As a disease, it is poorly characterized, and there is a weak evidence …