Alcoholic cardiomyopathy has been known for a long time, but there is little mechanistic
insight into this important clinical problem. The present study was undertaken using a mouse …

No data are currently available to directly support a causal relationship between alcohol
intake and CVD. As well-conducted randomized studies assessing the causal role of alcohol …

We recently discovered that regular alcohol consumption reduces ischemia-reperfusion
injury to the same degree as ischemic preconditioning in guinea pig hearts. Ischemic …

Alcohol is a known myocardial depressant. In a dose‐dependent fashion, one can show
progressive decline in left ventricular systolic function. This observation has been used to …

Objectives: The purpose of this study was to examine the cellular and molecular
mechanisms underlying alcoholic cardiomyopathy. Background: The mechanism for …

An extensive body of data shows concordant J-shaped associations between alcohol intake
and a variety of adverse health outcomes, including coronary heart disease, diabetes …

Background Alcohol drinking is an increasingly recognized risk factor for cardiovascular
disease. However, there are few studies of the impact of harmful and hazardous drinking on …

Ethanol has long been recognized as a toxic agent that has acute and chronic effects on
cerebral and hepatic function. Over the past two decades important influences on the …

Alcohol abuse can cause cardiomyopathy indistinguishable from other types of dilated
nonischemic cardiomyopathy. Most heavy drinkers remain asymptomatic in the earlier …

Some evidence suggests that light to moderate alcohol consumption protects against
cardiovascular diseases. However, this cardioprotective effect of alcohol consumption in …