Drug repurposing is at the heart of precision oncology. The move from tissue-or cancer-
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …

Drug repurposing refers to the identification of clinically approved drugs with the known
safety profiles and defined pharmacokinetic properties for new indications. Despite the …

Targeted drugs and precision medicine have transformed the landscape of cancer therapy
and significantly improved patient outcomes in many cases. However, as therapies are …

Ongoing new insights in the field of cancer diagnostics, genomic profiling, and cancer
behavior have raised the demand for novel, personalized cancer treatments. As the …

Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

Cancer is a leading cause of mortality worldwide and matters are only set to worsen as its
incidence continues to rise. Traditional approaches to combat cancer include improved …

The repositioning or “repurposing” of existing therapies for alternative disease indications is
an attractive approach that can save significant investments of time and money during drug …

Background Drug repurposing can speed up access to new therapeutic options for cancer
patients. With more than 2000 drugs approved worldwide and 6 relevant targets per drug on …

Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Many forms of cancer lack efficacious treatments, despite continuing advances in our
understanding of molecular biology, and the development of precisely targeted agents that …