Design, synthetic strategies, and therapeutic applications of heterofunctional glycodendrimers

L Mousavifar, R Roy - Molecules, 2021 - mdpi.com
Glycodendrimers have attracted considerable interest in the field of dendrimer sciences
owing to their plethora of implications in biomedical applications. This is primarily due to the …

Design, synthesis and potent pharmaceutical applications of glycodendrimers: a mini review

Y Li, Y Cheng, T Xu - Current drug discovery technologies, 2007 - ingentaconnect.com
Dendrimers are a new class of artifical macromolecules with well-defined hyperbranched
structures which endue these promising materials with a wide variety of applications. They …

Glycodendrimers: versatile tools for nanotechnology

R Roy, TC Shiao, K Rittenhouse-Olson - Brazilian Journal of …, 2013 - SciELO Brasil
Combining nanotechnology with glycobiology has triggered an exponential growth of
research activities in the design of novel functional bionanomaterials (glyconanotechnology) …

Design and synthesis of glycodendrimers

WB Turnbull, JF Stoddart - Reviews in Molecular Biotechnology, 2002 - Elsevier
Multivalent neoglycoconjugates with well-defined structures have considerable potential as
inhibitors of cell surface protein–carbohydrate interactions and as tools for studying such …

Recent trends in glycodendrimer syntheses and applications

YM Chabre, R Roy - Current topics in medicinal chemistry, 2008 - ingentaconnect.com
Carbohydrate protein interactions are at the front of several biological interactions spanning
from cell growth and differentiation, cell signaling, apoptosis, cancer, and microbial …

Glycodendrimers as functional antigens and antitumor vaccines

TC Shiao, R Roy - New Journal of Chemistry, 2012 - pubs.rsc.org
Glycodendrimers have advantageous characteristics of providing potent immunostimulating
and adjuvant properties in vaccine preparation due to their molecularly defined multivalent …

[引用][C] Toward the Synthesis of Large Oligosaccharide‐Based Dendrimers

WB Turnbull, AR Pease, JF Stoddart - ChemBioChem, 2000 - Wiley Online Library
It is now generally acknowledged that cell surface protein±carbohydrate interactions play a
crucial role in a wide range of biological processes [1] necessary for both normal …

“Onion peel” dendrimers: A straightforward synthetic approach towards highly diversified architectures

R Sharma, K Naresh, YM Chabre, R Rej… - Polymer …, 2014 - pubs.rsc.org
We report herein a novel “onion peel strategy” for the divergent construction of
glycodendrimers using different building blocks at each layer of the dendritic growth. A …

Synthesis of glycodendrimers with antiviral and antibacterial activity

P Hoyos, A Perona, O Juanes… - … A European Journal, 2021 - Wiley Online Library
Glycodendrimers are an important class of synthetic macromolecules that can be used to
mimic many structural and functional features of cell‐surface glycoconjugates. Their …

Multivalent glycoconjugate syntheses and applications using aromatic scaffolds

YM Chabre, R Roy - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycan–protein interactions are of utmost importance in several biological phenomena.
Although the variety of carbohydrate residues in mammalian cells is limited to less than a …