Circulating tumor cell analysis: technical and statistical considerations for application to the clinic

AL Allan, M Keeney - Journal of oncology, 2010 - Wiley Online Library
Solid cancers are a leading cause of death worldwide, primarily due to the failure of effective
clinical detection and treatment of metastatic disease in distant sites. There is growing …

Circulating tumor cells as promising novel biomarkers in solid cancers

ES Lianidou, A Strati, A Markou - Critical reviews in clinical …, 2014 - Taylor & Francis
The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a “liquid
biopsy” approach and has thus emerged lately as one of the hottest fields in cancer …

Circulating tumour cell detection on its way to routine diagnostic implementation?

S Sleijfer, JW Gratama, AM Sieuwerts, J Kraan… - European Journal of …, 2007 - Elsevier
Circulating tumour cells (CTCs) have been considered for a long time in reflecting the
aggressiveness of tumours. As a result, many attempts have been made to develop assays …

Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance

YF Sun, XR Yang, J Zhou, SJ Qiu, J Fan… - Journal of cancer research …, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have long been considered a reflection
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …

[HTML][HTML] Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid …

A Kowalik, M Kowalewska, S Góźdź - Translational Research, 2017 - Elsevier
Eight million people die of cancer each year and 90% of deaths are caused by systemic
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …

Circulating tumor cells

DF Hayes, JB Smerage - Progress in molecular biology and translational …, 2010 - Elsevier
Circulating tumor cells (CTCs) can be separated and characterized from normal
hematopoietic cellular constituents by a variety of methods. Different strategies have …

Recent advances in the molecular characterization of circulating tumor cells

LE Lowes, AL Allan - Cancers, 2014 - mdpi.com
Although circulating tumor cells (CTCs) were first observed over a century ago, lack of
sensitive methodology precluded detailed study of these cells until recently. However …

Circulating tumor cell detection technologies and clinical utility: Challenges and opportunities

Z Habli, W AlChamaa, R Saab, H Kadara, ML Khraiche - Cancers, 2020 - mdpi.com
The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and
management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate …

Isolation of rare circulating tumor cells in cancer patients: technical aspects and clinical implications

M Danova, M Torchio, G Mazzini - Expert review of molecular …, 2011 - Taylor & Francis
Circulating tumor cells (CTCs) may be detected in the blood of patients with epithelial tumors
using different analytical approaches. The relative number of CTCs is low and they include a …

Circulating tumor cells: overview and opportunities in cytology

KE Sundling, AC Lowe - Advances in anatomic pathology, 2019 - journals.lww.com
Circulating tumor cells (CTCs) have long been assumed to be the substrate of cancer
metastasis. However, only in recent years have we begun to leverage the potential of CTCs …