The mucus layer coating the gastrointestinal tract is the front line of innate host defense,
largely because of the secretory products of intestinal goblet cells. Goblet cells synthesize …

Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …

The membrane‐bound MUC1 mucin is expressed in normal mucosas and the aberrant
expression of its under‐glycosylated forms has been reported in carcinomas from different …

Background & Aims: Expression of mucin MUC2, the structural component of the colonic
mucus layer, is lowered in inflammatory bowel disease. Our aim was to obtain insight in the …

The MUC6 mucin has a critical protective function in the normal stomach, pancreas and
duodenum and is aberrantly expressed during the progression of some gastrointestinal …

The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has
different functions in normal and cancer cells. Owing to its structural and biochemical …

Mucins are high-molecular weight epithelial glycoproteins with a high content of clustered
oligosaccharides O-glycosidically linked to tandem repeat peptides rich in threonine, serine …

Mucus serves as the chief protective barrier against pathogenic and mechanical insults in
respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major …

The membrane-bound mucins belong to an ever-increasing family of O-glycoproteins.
Based on their structure and localization at the cell surface they are thought to play important …

Mucus is present throughout the gastrointestinal tract and is essential for regulating gut
microbiota homeostasis and preventing disease by protecting the gastrointestinal barrier …