New insights into drug repurposing for COVID-19 using deep learning

CY Lee, YPP Chen - IEEE Transactions on Neural Networks …, 2021 - ieeexplore.ieee.org
The coronavirus disease 2019 (COVID-19) has continued to spread worldwide since late
2019. To expedite the process of providing treatment to those who have contracted the …

Drug repurposing: a systematic review on root causes, barriers and facilitators

N Krishnamurthy, AA Grimshaw, SA Axson… - BMC health services …, 2022 - Springer
Background Repurposing is a drug development strategy receiving heightened attention
after the Food and Drug Administration granted emergency use authorization of several …

Using informative features in machine learning based method for COVID-19 drug repurposing

R Aghdam, M Habibi, G Taheri - Journal of cheminformatics, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a novel virus named Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus induced a large …

Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay

WD Jang, S Jeon, S Kim… - Proceedings of the …, 2021 - National Acad Sciences
The COVID-19 pandemic caused by SARS-CoV-2 is an unprecedentedly significant health
threat, prompting the need for rapidly developing antiviral drugs for the treatment. Drug …

A review on drug repurposing in COVID-19: From antiviral drugs to herbal alternatives

A Sezer, M Halilović-Alihodžić, AR Vanwieren… - Journal of Genetic …, 2022 - Springer
Background COVID-19 is an illness caused by severe acute respiratory syndrome
coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) …

Multi-omics and artificial intelligence-guided drug repositioning: prospects, challenges, and lessons learned from COVID-19

Y Cong, T Endo - OMICS: A Journal of Integrative Biology, 2022 - liebertpub.com
Drug repurposing is of interest for therapeutics innovation in many human diseases
including coronavirus disease 2019 (COVID-19). Methodological innovations in drug …

[HTML][HTML] Boosting the arsenal against COVID-19 through computational drug repurposing

G Ciliberto, L Cardone - Drug discovery today, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) world health emergency is calling scientists for
unprecedented, huge investigation efforts to urgently answer key questions: what is the …

Drug repurposing for rare diseases

HI Roessler, NVAM Knoers, MM van Haelst… - Trends in …, 2021 - cell.com
Currently, there are about 7000 identified rare diseases, together affecting 10% of the
population. However, fewer than 6% of all rare diseases have an approved treatment option …

Perspectives for repurposing drugs for the coronavirus disease 2019

SS Cherian, M Agrawal, A Basu… - Indian Journal of …, 2020 - journals.lww.com
The newly emerged 2019 novel coronavirus (CoV), named as severe acute respiratory
syndrome CoV-2 (SARS-CoV-2), like SARS-CoV (now, SARS-CoV-1) and Middle East …

“Hard” drug repurposing for precision oncology: the missing link?

P Pantziarka, G Bouche, N André - Frontiers in Pharmacology, 2018 - frontiersin.org
Drug repurposing is at the heart of precision oncology. The move from tissue-or cancer-
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …