Both cerebrovascular disease (CVD) and depression are common conditions in the elderly,
and there is emerging evidence of a bi-directional relationship: 1) depression can cause …

Major depressive disorders have recently been associated with impairments in signaling
pathways that regulate neuroplasticity and cell survival. Agents designed to directly target …

Objective To review the current evidence about the neurobiological mechanisms in major
depressive disorders (MDD) and the key findings from studies using neuroimaging tools and …

Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …

Depression after stroke is common. Although different opinions exist about the definition,
diagnosis, and measurement of outcomes related to depression after stroke, there is little …

The presence of neuropsychiatric disorders after stroke has been recognized for more than
100 years, but controlled systematic studies did not begin until the 1970s. The most clinically …

Background: This review summarizes recent findings in molecular biology and
neuroimaging and their applicability to the classification and identification of depression. We …

Depression is the world's leading cause of disability. Greater understanding of the
neurobiological basis of depression is necessary for developing novel treatments with …

As we approach the millennium, dramatic progress in our understanding and in our
treatment of mood disorders, among the oldest diseases known to mankind, is now a reality …

Major depressive disorders (MDD) are among the most debilitating diseases worldwide and
occur with a high prevalence in elderly individuals. Neurodegenerative diseases (in …