Regulatory T (Treg) cells play a crucial role in maintaining self‐tolerance and resolution of
immune responses by employing multifaceted immunoregulatory mechanisms. However …

Regulatory T cells (Tregs) are key immunosuppressive cells that promote tumor growth by
hindering the effector immune response. Tregs utilize multiple suppressive mechanisms to …

The immune system mediates powerful effector mechanisms to protect against a diversity of
pathogens and equally as important regulatory functions, to limit collateral damage of …

The success of immunotherapy in oncology underscores the vital role of the immune system
in cancer development. Regulatory T cells (Tregs) maintain a fine balance between …

Regulatory T (Treg) cells play a crucial role in maintaining peripheral tolerance and
preventing autoimmunity. However, they also represent a major barrier to effective antitumor …

Regulatory T (Treg) cells are found at elevated densities in many human cancers and are
thought to be a major barrier to the generation of robust antitumor T cell responses. In this …

Innate and adaptive immunity play important roles in immunosurveillance and tumor
destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may …

Regulatory T (Treg) cells maintain immune homeostasis by suppressing excessive immune
responses. Treg cells induce tolerance against self‐and foreign antigens, thus preventing …

The immune system has evolved complex effector mechanisms to protect the host against a
diversity of pathogenic organisms and regulatory adaptations that can curtail pathological …

Tumor cells evolve multiple sophisticated mechanisms to escape immune surveillance, one
of which is to establish tolerogenic microenvironment by recruiting certain immune …