Nerve regeneration restores supraspinal control of bladder function after complete spinal cord injury

YS Lee, CY Lin, HH Jiang, M DePaul… - Journal of …, 2013 - Soc Neuroscience
A life-threatening disability after complete spinal cord injury is urinary dysfunction, which is
attributable to lack of regeneration of supraspinal pathways that control the bladder …

Peripheral nerve transplantation combined with acidic fibroblast growth factor and chondroitinase induces regeneration and improves urinary function in complete …

MA DePaul, CY Lin, J Silver, YS Lee - PloS one, 2015 - journals.plos.org
The loss of lower urinary tract (LUT) control is a ubiquitous consequence of a complete
spinal cord injury, attributed to a lack of regeneration of supraspinal pathways controlling the …

Transplantation and repair: combined cell implantation and chondroitinase delivery prevents deterioration of bladder function in rats with complete spinal cord injury

K Fouad, DD Pearse, W Tetzlaff, R Vavrek - Spinal Cord, 2009 - nature.com
Study design: Additional examination. In this study, we report changes in bladder function
after a combined treatment that was designed to study axonal regeneration after complete …

Sprouting of CGRP primary afferents in lumbosacral spinal cord precedes emergence of bladder activity after spinal injury

NDT Zinck, VF Rafuse, JW Downie - Experimental neurology, 2007 - Elsevier
Spinal cord injury (SCI) severely disrupts bladder function. What mediates bladder
dysfunction after SCI is currently unknown. We investigated the role that primary afferent …

Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and …

T Mitsui, JS Shumsky, AC Lepore… - Journal of …, 2005 - Soc Neuroscience
Transplanting neuronal and glial restricted precursors (NRP/GRP) into a midthoracic injury 9
d after contusion improved bladder and motor function, diminished thermal hypersensitivity …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Multisystem neuroprosthetic training improves bladder function after severe spinal cord injury

M Horst, J Heutschi, R Van Den Brand… - The Journal of …, 2013 - auajournals.org
Severe spinal cord injury leads to neurogenic bladder dysfunction. We recently developed a
multisystem neuroprosthetic training program that promotes plastic changes capable of …

Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

O Ozsoy, U Ozsoy, G Stein, O Semler… - Restorative …, 2012 - content.iospress.com
Following spinal cord injury (SCI), loss of spinal and supraspinal control results in
desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter …

Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair

TX Hoang, V Pikov, LA Havton - Journal of Neuroscience, 2006 - Soc Neuroscience
Conus medullaris and/or cauda equina forms of spinal cord injury commonly result in a
permanent loss of bladder function. Here, we developed a cauda equina injury and repair …

Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury

V PIKOV, RA GILLIS, LUC JASMIN… - Journal of …, 1998 - liebertpub.com
Traumatic spinal cord injury (SCI) produces lower urinary tract (LUT) dysfunction that has
been studied in surgical transection models. Our aim was to assess LUT functional deficit in …