Dual pathway inhibition with rivaroxaban and aspirin reduces inflammatory biomarkers in atherosclerosis

V Russo, D Fabiani, S Leonardi, E Attena… - Journal of …, 2023 - journals.lww.com
Dual pathway inhibition (DPI) with low-dose rivaroxaban and aspirin in patients with
coronary artery disease (CAD) and/or peripheral artery disease (PAD) reduces the …

Novel antiplatelet agents: the current state and what is coming down the pike

F Franchi, F Rollini, Y Park, DJ Angiolillo - Progress in Cardiovascular …, 2015 - Elsevier
Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary
syndrome (ACS) or undergoing percutaneous coronary intervention (PCI). Despite the use …

Systematic review with meta‐analysis: the risk of gastrointestinal bleeding in patients taking third‐generation P2Y12 inhibitors compared with clopidogrel

CG Guo, L Chen, EW Chan, KS Cheung… - Alimentary …, 2019 - Wiley Online Library
Background Ticagrelor and prasugrel are third‐generation oral P2Y12 receptor antagonists
with rapid onset and pronounced platelet inhibition. However, higher overall bleeding rates …

Use of dual antiplatelet therapy and patient outcomes in those undergoing percutaneous coronary intervention: the ROCKET AF trial

MW Sherwood, DD Cyr, WS Jones, RC Becker… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The authors assessed the use of dual antiplatelet therapy (DAPT) and outcomes
in patients undergoing percutaneous coronary intervention (PCI) during the ROCKET AF …

Low-dose rivaroxaban: can cardiovascular events be reduced?

L De Luca - European Heart Journal Supplements, 2023 - academic.oup.com
Despite available effective guideline-based preventive therapies, patients with vascular
diseases remain at high-risk of recurrent ischaemic events. Novel therapeutic strategies are …

Emerging antiplatelet agents, differential pharmacology, and clinical utility

P Das, CS Oliphant, E Beach, R Thapa - Journal of blood medicine, 2010 - Taylor & Francis
The aspirin–clopidogrel combination is the current gold standard antiplatelet regimen
following percutaneous coronary intervention and for the treatment of acute coronary …

Chronic kidney disease has a significant impact on platelet inhibition of new P2Y12 inhibitors

P Deharo, M Pankert, J Quilici… - International …, 2015 - internationaljournalofcardiology.com
Dual antiplatelet therapy using aspirin and a platelet P2Y12 receptor inhibitor is a
cornerstone therapy for acute coronary syndrome (ACS)[1]. Since clopidogrel has proved his …

Overview of pleiotropic effects of platelet P2Y12 receptor inhibitors

P Adamski, M Koziński, M Ostrowska… - Thrombosis and …, 2014 - thieme-connect.com
Dual antiplatelet therapy consisting of one of the P2Y12 receptor inhibitors in conjunction
with aspirin is the mainstay of treatment for patients with acute coronary syndromes (ACS) …

2017 ESC guidelines focus on dual antiplatelet therapy

GMC Rosano, P Seferovic - European Heart Journal …, 2018 - academic.oup.com
Dual antiplatelet therapy (DAPT), or the combination of aspirin and an oral inhibitor of the
platelet P2Y12 receptor, is indicated in acute coronary syndromes (ACS) and after …

Third generation P2Y12 antagonists inhibit platelet aggregation more effectively than clopidogrel in a myocardial infarction registry

CB Olivier, P Diehl, K Schnabel, P Weik… - Thrombosis and …, 2014 - thieme-connect.com
The current standard of antiplatelet therapy of patients after myocardial infarction includes
the P2Y 12 receptor antagonists clopidogrel, prasugrel or ticagrelor. This study aimed to …