Emerging antiplatelet agents, differential pharmacology, and clinical utility
P Das, CS Oliphant, E Beach, R Thapa - Journal of blood medicine, 2010 - Taylor & Francis
The aspirin–clopidogrel combination is the current gold standard antiplatelet regimen
following percutaneous coronary intervention and for the treatment of acute coronary …
following percutaneous coronary intervention and for the treatment of acute coronary …
2017 ESC guidelines focus on dual antiplatelet therapy
GMC Rosano, P Seferovic - European Heart Journal …, 2018 - academic.oup.com
Dual antiplatelet therapy (DAPT), or the combination of aspirin and an oral inhibitor of the
platelet P2Y12 receptor, is indicated in acute coronary syndromes (ACS) and after …
platelet P2Y12 receptor, is indicated in acute coronary syndromes (ACS) and after …
[HTML][HTML] De-escalation of antiplatelet therapy in acute coronary syndromes: why, how and when?
M Galli, DJ Angiolillo - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
The synergistic blockade of the key platelet signaling pathways of cyclooxygenase-1
blockade and P2Y12 signaling by combining aspirin plus a potent P2Y12 inhibitor …
blockade and P2Y12 signaling by combining aspirin plus a potent P2Y12 inhibitor …
Third generation P2Y12 antagonists inhibit platelet aggregation more effectively than clopidogrel in a myocardial infarction registry
CB Olivier, P Diehl, K Schnabel, P Weik… - Thrombosis and …, 2014 - thieme-connect.com
The current standard of antiplatelet therapy of patients after myocardial infarction includes
the P2Y 12 receptor antagonists clopidogrel, prasugrel or ticagrelor. This study aimed to …
the P2Y 12 receptor antagonists clopidogrel, prasugrel or ticagrelor. This study aimed to …
Overview of pleiotropic effects of platelet P2Y12 receptor inhibitors
P Adamski, M Koziński, M Ostrowska… - Thrombosis and …, 2014 - thieme-connect.com
Dual antiplatelet therapy consisting of one of the P2Y12 receptor inhibitors in conjunction
with aspirin is the mainstay of treatment for patients with acute coronary syndromes (ACS) …
with aspirin is the mainstay of treatment for patients with acute coronary syndromes (ACS) …
P2Y12 receptor antagonists: which one to choose? A systematic review and meta-analysis
Background: Pharmacological properties of the currently available P2Y12 receptor
antagonists differ significantly and lead to different degrees of platelets inhibition and …
antagonists differ significantly and lead to different degrees of platelets inhibition and …
[HTML][HTML] Bleeding complications with clopidogrel or ticagrelor in ST-elevation myocardial infarction patients–A real life cohort study of two treatment strategies
J Alfredsson, K Omar, J Csog, D Venetsanos… - IJC Heart & …, 2020 - Elsevier
Introduction Dual antiplatelet therapy (DAPT), including potent P2Y12 inhibition after ST-
elevation myocardial infarction (STEMI) is recommended in clinical guidelines. However …
elevation myocardial infarction (STEMI) is recommended in clinical guidelines. However …
Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function
HM Judge, RJ Buckland, A Sugidachi… - Thrombosis and …, 2010 - thieme-connect.com
The thienopyridine P2Y 12 receptor antagonists clopidogrel and prasugrel prevent arterial
thrombosis and are routinely used following percutaneous coronary intervention. However …
thrombosis and are routinely used following percutaneous coronary intervention. However …
Platelet thrombin receptor antagonism and atherothrombosis
DJ Angiolillo, D Capodanno, S Goto - European heart journal, 2010 - academic.oup.com
Clinical manifestations of atherothrombotic disease, such as acute coronary syndromes,
cerebrovascular events, and peripheral arterial disease, are major causes of mortality and …
cerebrovascular events, and peripheral arterial disease, are major causes of mortality and …
[HTML][HTML] De-Escalation of Platelet P2Y12 Receptor Inhibiting Therapy After Percutaneous Coronary Intervention: Does One Size Fit All?
Oral platelet P2Y12 receptor inhibitors (clopidogrel, prasugrel, ticagrelor), used in adjunct to
aspirin, are key in reducing ischemic events among patients with acute coronary syndrome …
aspirin, are key in reducing ischemic events among patients with acute coronary syndrome …