P2Y12 inhibition in high bleeding risk patients: making the right decision in a complex setting
K Dimitriadis, N Pyrpyris, K Aznaouridis… - European Heart …, 2023 - academic.oup.com
We read with great interest the SWEDEHEART report by Tjerkaski et al. 1 regarding the
comparison of ticagrelor vs. clopidogrel in patients with myocardial infarction (MI) and high …
comparison of ticagrelor vs. clopidogrel in patients with myocardial infarction (MI) and high …
Antiplatelet therapy aims and strategies in Asian patients with acute coronary syndrome or stable coronary artery disease
Dual antiplatelet therapy (DAPT) has been the mainstay treatment to reduce ischemic
events, such as myocardial infarction or stroke, in patients with coronary artery disease …
events, such as myocardial infarction or stroke, in patients with coronary artery disease …
Safety and efficacy of different P2Y12 inhibitors in patients with acute coronary syndromes stratified by the PRAISE risk score: a multicentre study
G Patti, F D'Ascenzo, O De Filippo… - … Journal-Quality of …, 2022 - academic.oup.com
Aims To establish the safety and efficacy of different dual antiplatelet therapy (DAPT)
combinations in patients with acute coronary syndrome (ACS) according to their baseline …
combinations in patients with acute coronary syndrome (ACS) according to their baseline …
Guided and unguided de-escalation from potent P2Y12 inhibitors among patients with acute coronary syndrome: a meta-analysis
AH Tavenier, R Mehran, M Chiarito… - European Heart …, 2022 - academic.oup.com
Aim Optimal dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary
intervention (PCI) for acute coronary syndrome (ACS) intends to balance ischemic and …
intervention (PCI) for acute coronary syndrome (ACS) intends to balance ischemic and …
Impact of P2Y12 inhibitory effects induced by clopidogrel on platelet procoagulant activity in type 2 diabetes mellitus patients
DJ Angiolillo, P Capranzano, B Desai… - Thrombosis research, 2009 - Elsevier
INTRODUCTION: Type 2 diabetes mellitus (T2DM) patients have a variable response profile
to the P2Y12 receptor antagonist clopidogrel. P2Y12 receptor signalling promotes platelet …
to the P2Y12 receptor antagonist clopidogrel. P2Y12 receptor signalling promotes platelet …
Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease
D Capodanno, DL Bhatt, JW Eikelboom… - Nature Reviews …, 2020 - nature.com
Advances in antiplatelet therapies for patients with cardiovascular disease have improved
patient outcomes over time, but the challenge of balancing the risks of ischaemia and …
patient outcomes over time, but the challenge of balancing the risks of ischaemia and …
Platelet inhibition agents: current and future P2Y12 receptor antagonists
J Tang, MP Li, HH Zhou… - Current Vascular …, 2015 - ingentaconnect.com
Percutaneous coronary intervention is widely used to reduce the risk of death or
cardiovascular events in patients with acute coronary syndromes. Dual antiplatelet treatment …
cardiovascular events in patients with acute coronary syndromes. Dual antiplatelet treatment …
Comparison of pharmacodynamic effects of ticagrelor vs prasugrel in type 2 diabetes mellitus patients with coronary heart disease
LL Shang, DD Guo, HY Zhao, AJ Quan… - Journal of clinical …, 2018 - Wiley Online Library
What is known and objective Patients with type 2 diabetes mellitus (T2DM) are at higher risk
of thrombotic complications. Studies have indicated that patients with T2DM have impaired …
of thrombotic complications. Studies have indicated that patients with T2DM have impaired …
Still a long way to the precision medicine of antiplatelet strategy after percutaneous coronary intervention
YH Jeong, Y Obayashi, H Song… - Circulation …, 2022 - Am Heart Assoc
Antiplatelet therapy is essential to reduce athero-thrombotic events in patients undergoing
percutaneous coronary intervention (PCI), but this strategy is inevitably associated with an …
percutaneous coronary intervention (PCI), but this strategy is inevitably associated with an …