Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF‐β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast …

N Selvamurugan, Z He, D Rifkin… - Stem cells …, 2017 - Wiley Online Library
Pulsed electromagnetic fields (PEMFs) have been documented to promote bone fracture
healing in nonunions and increase lumbar spinal fusion rates. However, the molecular …

Pulsed electromagnetic fields increase osteogenetic commitment of MSCs via the mTOR pathway in TNF-α mediated inflammatory conditions: An in-vitro study

L Ferroni, C Gardin, O Dolkart, M Salai, S Barak… - Scientific reports, 2018 - nature.com
Pulsed electromagnetic fields (PEMFs) have been considered a potential treatment modality
for fracture healing, however, the mechanism of their action remains unclear. Mammalian …

Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study

JHW Jansen, OP van der Jagt, BJ Punt… - BMC musculoskeletal …, 2010 - Springer
Background Although pulsed electromagnetic field (PEMF) stimulation may be clinically
beneficial during fracture healing and for a wide range of bone disorders, there is still debate …

Pulsed electromagnetic fields promote in vitro osteoblastogenesis through a Wnt/β‐catenin signaling‐associated mechanism

M Zhai, D Jing, S Tong, Y Wu, P Wang… - …, 2016 - Wiley Online Library
Substantial evidence indicates that pulsed electromagnetic fields (PEMF) could accelerate
fracture healing and enhance bone mass, whereas the unclear mechanism by which PEMF …

A Comparative Analysis of the In Vitro Effects of Pulsed Electromagnetic Field Treatment on Osteogenic Differentiation of Two Different Mesenchymal Cell Lineages

G Ceccarelli, N Bloise, M Mantelli… - BioResearch open …, 2013 - liebertpub.com
Human mesenchymal stem cells (MSCs) are a promising candidate cell type for
regenerative medicine and tissue engineering applications. Exposure of MSCs to physical …

Pulsed electromagnetic fields stimulate osteogenic differentiation in human bone marrow and adipose tissue derived mesenchymal stem cells

A Ongaro, A Pellati, L Bagheri, C Fortini… - …, 2014 - Wiley Online Library
Pulsed electromagnetic fields (PEMFs) play a regulatory role on osteoblast activity and are
clinically beneficial during fracture healing. Human mesenchymal stem cells (MSCs) derived …

Intermittent pulsed electromagnetic field stimulation activates the mTOR pathway and stimulates the proliferation of osteoblast‐like cells

H Miyamoto, Y Sawaji, T Iwaki, T Masaoka… - …, 2019 - Wiley Online Library
Pulsed electromagnetic fields (PEMFs) have been shown to be a noninvasive physical
stimulant for bone fracture healing. However, PEMF stimulation requires a relatively long …

Pulsed electromagnetic field induces Ca2+-dependent osteoblastogenesis in C3H10T1/2 mesenchymal cells through the Wnt-Ca2+/Wnt-β-catenin signaling pathway

S Wu, Q Yu, A Lai, J Tian - Biochemical and biophysical research …, 2018 - Elsevier
Pulsed electromagnetic fields (PEMFs) are effective in healing fractures and improving
osteoporosis. However, their effect on mesenchymal cells remains largely unknown. In this …

Effects of electromagnetic field on proliferation, differentiation, and mineralization of MC3T3 cells

L Suryani, JH Too, AM Hassanbhai, F Wen… - … Engineering Part C …, 2019 - liebertpub.com
The steep increasing incidence of bone diseases and fractures provides a commanding
impetus and growing demands for bone tissue engineering research. Pulsed …

Pulsed electromagnetic fields inhibit human osteoclast formation and gene expression via osteoblasts

Z He, N Selvamurugan, J Warshaw, NC Partridge - Bone, 2018 - Elsevier
Pulsed electromagnetic fields (PEMFs) can be effective in promoting the healing of delayed
union or nonunion fractures. We previously reported that PEMF (Spinal-Stim® by Orthofix …