Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin
resistance and dyslipidemia. Research on its involvement in cardiovascular diseases has …

Growing evidence suggests that ceramides play an important role in the development of
atherosclerotic and valvular heart disease. Ceramides are biologically active sphingolipids …

Ceramides, composed of a sphingosine and a fatty acid, are bioactive lipid molecules
involved in many key cellular pathways (eg, apoptosis, oxidative stress and inflammation) …

Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …

Ceramides are bioactive lipids that act as secondary messengers for both intra-and inter-
cellular signaling. Elevated plasma concentrations of ceramides are associated with multiple …

There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the
main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have …

Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs
have been met and its nutrient storage has reached capacity. As these sphingolipids accrue …

Ceramides are a family of lipid molecules, composed of sphingosine and a fatty acid, and
transported by lipoproteins (primarily by low-density lipoproteins) in the bloodstream. They …

Ceramides are sphingolipids and integral components of the eukaryotic cell membrane.
Apart from providing structural integrity, ceramides have also been shown to act as second …

The global prevalence of metabolic diseases such as type 2 diabetes mellitus,
steatohepatitis, myocardial infarction, and stroke has increased dramatically over the past …