[HTML][HTML] The immune response to acute focal cerebral ischemia and associated post-stroke immunodepression: a focused review

BM Famakin - Aging and Disease, 2014 - ncbi.nlm.nih.gov
It is currently well established that the immune system is activated in response to transient or
focal cerebral ischemia. This acute immune activation occurs in response to damage, and …

Therapeutically targeting neuroinflammation and microglia after acute ischemic stroke

Y Lee, SR Lee, SS Choi, HG Yeo… - BioMed research …, 2014 - Wiley Online Library
Inflammation has a pivotal role in the pathogenesis of ischemic stroke, and recent studies
posit that inflammation acts as a double‐edged sword, not only detrimentally augmenting …

Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management

L Ramiro, A Simats… - Therapeutic …, 2018 - journals.sagepub.com
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide.
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …

Inflammation in ischemic brain injury: timing is important

J Kriz - Critical reviews™ in Neurobiology, 2006 - dl.begellhouse.com
Inflammation is a defense reaction against diverse insults that serves to remove noxious
agents and to limit their detrimental effects. There is increasing evidence that post-ischemic …

Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?

AR Saand, F Yu, J Chen… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …

Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target

A Denes, E Pinteaux, NJ Rothwell… - Cerebrovascular Diseases, 2011 - karger.com
Inflammation is established as a contributor to cerebrovascular disease. Risk factors for
stroke include many conditions associated with chronic or acute inflammation, and …

New insight into neutrophils: a potential therapeutic target for cerebral ischemia

R Chen, X Zhang, L Gu, H Zhu, Y Zhong, Y Ye… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke is one of the main issues threatening human health worldwide, and it is also
the main cause of permanent disability in adults. Energy consumption and hypoxia after …

Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

Molecular and cellular immune responses to ischemic brain injury

HA Seifert, KR Pennypacker - Translational stroke research, 2014 - Springer
Despite extensive research into stroke pathology, there have not been any major recent
advancements in stroke therapeutics. Animal models of cerebral ischemia and clinical data …

Immune mechanisms of stroke

T Magnus, H Wiendl, C Kleinschnitz - Current opinion in …, 2012 - journals.lww.com
Immune mechanisms of stroke : Current Opinion in Neurology Immune mechanisms of
stroke : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …