BACKGROUND Little is known about the genomic differences between metastatic lower
tract urothelial carcinoma (LTUC) and upper tract urothelial carcinoma (UTUC). We compare …

Recent molecular characterization of primary urothelial carcinoma (UC) may guide future
clinical decision-making. For metastatic UC (mUC), a comprehensive molecular …

BACKGROUND Biomarker‐guided clinical trials are increasingly common in metastatic
urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not …

Abstract Urothelial Cancer-Genomic Analysis to Improve Patient Outcomes and Research
(NCT02643043), UC-GENOME, is a genomic analysis and biospecimen repository study in …

Background Upper urinary tract urothelial cancer (UTUC) may have unique etiologic and
genomic factors compared to bladder cancer. Objective To characterize the genomic …

Backgrounds Urothelial carcinoma (UC) is the most common genitourinary malignancy in
China. In this study, we surveyed the genomic features in Chinese UC patients and …

Backgrounds Despite the genomic landscape of urothelial carcinomas (UC) patients,
especially those with UC of bladder (UCB), has been comprehensively delineated and …

The molecular characteristics of metastatic upper tract urothelial carcinoma (UTUC) are not
well understood, and there is a lack of knowledge regarding the genomic and transcriptomic …

PURPOSE: A better understanding of the molecular basis of urothelial carcinoma (UC) is
needed to refine the clinical decision-making process. METHODS AND MATERIALS: We …

Background Characterization of the different genomic alterations (GAs) in urothelial
carcinoma (UC), by site of origin, may identify contrasting therapeutic opportunities and …