The fatty acid transport function of fatty acid-binding proteins

J Storch, AEA Thumser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2000 - Elsevier
The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …

Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome

E Erbay, H Cao, GS Hotamisligil - Current atherosclerosis reports, 2007 - Springer
The link between inflammation and the development of insulin resistance, type 2 diabetes,
and atherosclerosis has been uncovered in the past decade. Although the molecular …

Identification of a human heart FABP pseudogene located on chromosome 13

CFM Prinsen, DO Weghuis, AG van Kessel… - Gene, 1997 - Elsevier
The fatty acid-binding proteins (FABPs) constitute a conserved group of cytosolic low
molecular mass proteins, which consists of several types: liver, heart, myelin, epidermal …

Direct comparison of mice null for liver or intestinal fatty acid-binding proteins reveals highly divergent phenotypic responses to high fat feeding

AM Gajda, YX Zhou, LB Agellon, SK Fried… - Journal of Biological …, 2013 - ASBMB
The enterocyte expresses two fatty acid-binding proteins (FABP), intestinal FABP (IFABP;
FABP2) and liver FABP (LFABP; FABP1). LFABP is also expressed in liver. Despite ligand …

Bile salt recognition by human liver fatty acid binding protein

F Favretto, C Santambrogio, M D'Onofrio… - The FEBS …, 2015 - Wiley Online Library
Fatty acid binding proteins (FABP s) act as intracellular carriers of lipid molecules, and play
a role in global metabolism regulation. Liver FABP (L‐FABP) is prominent among FABP s for …

[引用][C] Fatty acid-binding proteins: structural and functional diversity

JH Veerkamp, RGHJ Maatman… - Biochemical Society …, 1992 - portlandpress.com
Fatty acids are important molecules for all cells either as energy-delivering substrates or as
precursors for synthesis of membrane lipids and lipid mediators such as thromboxanes …

Properties and physiological significance of fatty acid binding proteins

NH Haunerland, F Spener - Advances in Molecular and Cell Biology, 2003 - Elsevier
Publisher Summary This chapter discusses the properties and physiological significance of
fatty acid binding properties. Fatty acid binding proteins (FABP) are found in many tissues of …

Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid …

F Zhang, C Lücke, LJ Baier, JC Sacchettini… - Biochemistry, 2003 - ACS Publications
The human intestinal fatty acid binding protein (I-FABP) belongs to a family of intracellular
lipid binding proteins. This 15 kDa protein binds dietary long-chain fatty acids in the cytosol …

Identification of a functional polymorphism at the adipose fatty acid binding protein gene (FABP4) and demonstration of its association with cardiovascular disease: a …

JM Ordovas - Nutrition reviews, 2007 - academic.oup.com
Fatty acid binding proteins (FABPs) are proteins that reversibly bind fatty acids and other
lipids. So far, nine tissue-specific cytoplasmic FABPs have been identified. Adipose tissue …

Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligands

RA Weisiger - Cellular Lipid Binding Proteins, 2002 - Springer
Cytosolic long-chain fatty acid binding proteins (FABPs) are found in tissues that metabolize
fatty acids. Like most lipid binding proteins, their specific functions remain unclear. Two …