Randomized phase II study of bevacizumab in combination with chemotherapy in previously untreated extensive-stage small-cell lung cancer: results from the …

DR Spigel, PM Townley, DM Waterhouse… - Journal of clinical …, 2011 - ascopubs.org
Purpose Because of promising efficacy signals in single-arm studies, a placebo-controlled,
double-blind, randomized phase II trial was designed to assess the efficacy and safety of …

Phase II study of cisplatin plus etoposide and bevacizumab for previously untreated, extensive-stage small-cell lung cancer: Eastern Cooperative Oncology Group …

L Horn, SE Dahlberg, AB Sandler, A Dowlati… - Journal of clinical …, 2009 - ascopubs.org
Purpose To investigate the efficacy and safety of bevacizumab plus cisplatin and etoposide
in patients with extensive-stage disease, small-cell lung cancer (ED-SCLC). Patients and …

[HTML][HTML] Randomized phase II–III study of bevacizumab in combination with chemotherapy in previously untreated extensive small-cell lung cancer: results from the …

JL Pujol, A Lavole, E Quoix, O Molinier, PJ Souquet… - Annals of …, 2015 - Elsevier
ABSTRACT IFCT study administering 7.5 mg/kg Bevacizumab plus chemotherapy after
chemotherapy induction did not improve outcomes in extensive SCLC patients. Background …

[HTML][HTML] Phase II trial of irinotecan, carboplatin, and bevacizumab in the treatment of patients with extensive-stage small-cell lung cancer

DR Spigel, FA Greco, JD Zubkus, PB Murphy… - Journal of Thoracic …, 2009 - Elsevier
Introduction Bevacizumab's role in the treatment of small cell lung cancer (SCLC) is
unknown. A multicenter phase II trial with bevacizumab plus chemotherapy was conducted …

Italian, multicenter, phase III, randomized study of cisplatin plus etoposide with or without bevacizumab as first-line treatment in extensive-disease small-cell lung …

M Tiseo, L Boni, F Ambrosio, A Camerini… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Considering promising results in phase II studies, a randomized phase III trial was
designed to assess the efficacy of adding bevacizumab to first-line cisplatin plus etoposide …

Cisplatin, irinotecan, and bevacizumab for untreated extensive-stage small-cell lung cancer: CALGB 30306, a phase II study

NE Ready, AZ Dudek, HH Pang… - Journal of clinical …, 2011 - ascopubs.org
Purpose The efficacy of cisplatin, irinotecan, and bevacizumab was evaluated in patients
with extensive-stage small-cell lung cancer (ES-SCLC). Patients and Methods Patients with …

Randomized phase II trial of cisplatin and etoposide in combination with veliparib or placebo for extensive-stage small-cell lung cancer: ECOG-ACRIN 2511 study

TK Owonikoko, SE Dahlberg, GL Sica… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Veliparib, a poly (ADP ribose) polymerase inhibitor, potentiated standard
chemotherapy against small-cell lung cancer (SCLC) in preclinical studies. We evaluated …

Comparison of first-line treatments for patients with extensive-stage small cell lung cancer: a systematic review and network meta-analysis

T Zhou, Z Zhang, F Luo, Y Zhao, X Hou, T Liu… - JAMA network …, 2020 - jamanetwork.com
Importance Combinations of chemotherapy with immunotherapy or bevacizumab in first-line
treatments of extensive-stage small cell lung cancer (ES-SCLC) have been evaluated in …

Veliparib in combination with carboplatin and etoposide in patients with treatment-naïve extensive-stage small cell lung cancer: a phase 2 randomized study

LA Byers, D Bentsion, S Gans, K Penkov, CH Son… - Clinical Cancer …, 2021 - AACR
Purpose: This study investigated the efficacy and safety of oral PARP inhibitor veliparib, plus
carboplatin and etoposide in patients with treatment-naïve, extensive-stage small cell lung …

Carboplatin-or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data

A Rossi, M Di Maio, P Chiodini, RM Rudd… - Journal of Clinical …, 2012 - ascopubs.org
Purpose Since treatment efficacy of cisplatin-or carboplatin-based chemotherapy in the first-
line treatment of small-cell lung cancer (SCLC) remains contentious, a meta-analysis of …