Photon migration in highly scattering tissues such as muscle and brain gives optical
pathlengths that are dependent upon absorption and scattering parameters, μ a μ s' …

We have designed and constructed a near-infrared spectrometer for the non-invasive optical
study of biological tissue. This instrument works in the frequency-domain and employs …

The accurate, quantitative analysis of absorption and scattering properties in tissue is a
central problem in biochemical optics, in particular for the determination of hemoglobin and …

Natural pigments such as hemoglobin, myoglobin, and the cytochromes have characteristic
absorption spectra. Spectrophotometry methods are useful tools to observe in vivo changes …

The optical study of tissues began with the spectroscopic studies of Glenn Millikan in 1935
who proposed a “metabolic microscope” by which he would follow metabolic demand as …

The recent development of near-infrared time-and frequency-resolved tissue spectroscopy
techniques to probe tissue oxygenation and tissue oxygenation kinetics has led to the need …

A simple method to evaluate the hemoglobin oxygen saturation and relative hemoglobin
concentration in a tissue from diffuse reflectance spectra in the visible wavelength range is …

A set of equations derived to describe the optics of highly scattering materials are explained,
extended, and applied to the problem of in vitro and in vivo measurement of the relative …

It is a great pleasure to honor Dr. Thews. I am going to talk about two aspects of his works,
the optical method and the diffusion process. In the 1870's, Tyndall devised the dual …

Difficulties of quantitation of hemoglobin/myoglobin absorption changes in muscle have led
to the development of a new approach using short pulses of light. This method uses input …