Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments

T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …

The dendritic tree and brain disorders

VA Kulkarni, BL Firestein - Molecular and Cellular Neuroscience, 2012 - Elsevier
Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite arbors, and dendritic …

Dendritic structural plasticity and neuropsychiatric disease

MP Forrest, E Parnell, P Penzes - Nature Reviews Neuroscience, 2018 - nature.com
The structure of neuronal circuits that subserve cognitive functions in the brain is shaped
and refined throughout development and into adulthood. Evidence from human and animal …

Dendrite morphogenesis from birth to adulthood

CL Prigge, JN Kay - Current opinion in neurobiology, 2018 - Elsevier
Highlights•A switch from radial migration to dendrite initiation is regulated by local
cues.•Dendrites can select backup synaptic partners when their first choice is missing.•Some …

Cell-intrinsic drivers of dendrite morphogenesis

SV Puram, A Bonni - Development, 2013 - journals.biologists.com
The proper formation and morphogenesis of dendrites is fundamental to the establishment
of neural circuits in the brain. Following cell cycle exit and migration, neurons undergo …

Mechanisms regulating dendritic arbor patterning

F Ledda, G Paratcha - Cellular and Molecular Life Sciences, 2017 - Springer
The nervous system is populated by diverse types of neurons, each of which has dendritic
trees with strikingly different morphologies. These neuron-specific morphologies determine …

Analysis of dendritic spine morphology in cultured CNS neurons

DP Srivastava, KM Woolfrey, P Penzes - JoVE (Journal of Visualized …, 2011 - jove.com
Dendritic spines are the sites of the majority of excitatory connections within the brain, and
form the post-synaptic compartment of synapses. These structures are rich in actin and have …

Dendritic spine alterations in schizophrenia

CE Moyer, MA Shelton, RA Sweet - Neuroscience letters, 2015 - Elsevier
Schizophrenia is a chronic illness affecting approximately 0.5–1% of the world's population.
The etiology of schizophrenia is complex, including multiple genes, and contributing …

Molecular mechanisms of dendrite stability

AJ Koleske - Nature Reviews Neuroscience, 2013 - nature.com
In the developing brain, dendrite branches and dendritic spines form and turn over
dynamically. By contrast, most dendrite arbors and dendritic spines in the adult brain are …

[HTML][HTML] Molecular mechanisms of dendrite morphogenesis

J Arikkath - Frontiers in cellular neuroscience, 2012 - frontiersin.org
Dendrites are key integrators of synaptic information in neurons and play vital roles in
neuronal plasticity. Hence, it is necessary that dendrite arborization is precisely controlled …