Dynamic hyperinflation (DH) is a major pathophysiologic consequence of airflow limitation
during exercise in patients with chronic obstructive pulmonary disease (COPD) and an …

It is unknown whether central hemodynamics are impaired during exercise in chronic
obstructive pulmonary disease (COPD) patients. We hypothesized that, at a similar absolute …

BACKGROUND In COPD, a decreased inspiratory capacity to total lung capacity ratio
(IC/TLC) is associated with dynamic hyperinflation and poor exercise capacity. The …

In contrast to the decline in FEV1, the behavior of dynamic hyperinflation (DH) over time is
unknown in patients with COPD. Metronome-paced hyperventilation (MPH) is a simple …

BACKGROUND: Exercise intolerance is the hallmark of COPD. Static lung hyperinflation
and increased dynamic hyperinflation during exercise are associated with reduced …

Background Current measures of tidal volume/forced vital capacity (VT/FVC) and
VT/inspiratory capacity (VT/IC) at peak exercise cannot differentiate restrictive from …

BACKGROUND: Physical activity and health status deteriorate early in the course of chronic
obstructive pulmonary disease (COPD). This can only partially be explained by the degree …

Purpose: To investigate the correlation between a plateau in minute ventilation E during
cardiopulmonary exercise tests (CPETs) and its impact on cardiac performance. Methods …

Rationale: Although the major limitation to exercise performance in patients with COPD is
dynamic hyperinflation, little is known about its relation to daily physical activity. Objectives …

Background Dynamic hyperinflation (DH) is a major contributor to exercise limitation in
chronic obstructive pulmonary disease (COPD). Therefore, we aimed to elucidate the …