To determine if a remodeling of the collagen matrix would occur in the absence of
hypertrophy and cell necrosis and if such a remodeling could alter active and passive …

To determine whether regression of hypertensive hypertrophy through blood pressure
control also involves left ventricular collagen and consecutive alterations in left ventricular …

This article reports on the effects of captopril on both the prevention and the regression of
myocardial cell hypertrophy and interstitial fibrosis in experimental animals (rats) with …

Objective To determine whether antihypertensive treatment could alter hypertension and
age-related progressive impairment of coronary hemodynamics and cardiac fibrosis in aged …

Fibrosis impairs cardiac function. This project has determined the expression and deposition
of collagens and fibronectin and cardiac function in the deoxycorticosterone acetate (DOCA) …

The aim of this study was to clarify how collagen deposition or medial hypertrophy of the
vascular wall affects the coronary dilator reserve in pressure-overloaded hearts and whether …

An alteration in the rate of collagen synthesis was observed in spontaneously hypertensive
rats during evolution of hypertension. An increase in rate of synthesis of collagen and a …

Study objective–The aim was to compare the temporal sequence and structural relationship
between perivascular and interstitial fibrosis and microscopic scarring seen in the left …

The myocardium contains myocyte and non-myocyte cells. A disproportionate growth of the
nonmyocyte cell population can alter myocardial structure and lead to pathologic …

The myocardium contains a fibrillar collagen matrix that consists primarily of type I and type
III collagens. There is a marked alteration in the ratio and amount of collagen phenotypes in …