Aim: To investigate hypoxia-inducible factor-1α (HIF-1α) and histone methylation markers as
potential indicators of prognosis in esophageal squamous cell carcinoma (ESCC). Patients …

In colon cancer, the prognostic value of macrophages is controversial, and it is still unknown
how hypoxia modulates macrophage–cancer cell crosstalk. To unravel this, co-cultures of …

Abstract Hypoxia-inducible factor-1α (HIF-1α) and toll-like receptor 4 (TLR4) are involved in
numerous mechanisms of cancer biology, including cell proliferation and survival; however …

In colon cancer, the prognostic value of macrophages is controversial, and it is still unknown
how hypoxia modulates macrophage–cancer cell crosstalk. To unravel this, co-cultures of …

Hypoxia is a common feature of many solid tumors, including hepatocellular carcinoma
(HCC). Hypoxia can promote tumor progression and induce radiation and chemotherapy …

Hypoxia inducible factor 1 (HIF-1) is a transcription factor composed of two subunits, namely,
HIF-1α and HIF-1β, in which HIF-1β is constitutively expressed. HIF-1 upregulates several …

The role of HIF-2α in hepatocellular carcinoma (HCC) is unclear. The aim of the present
study was to investigate the expression pattern and role of HIF-2α in HCC patients …

Hypoxia-inducible factor-1 (HIF-1) is a major determinant of invasion and metastasis in
several tumor types. We previously reported that HIF-1α contributed to multidrug resistance …

The complex cross‐talk of intricate intercellular signaling networks between the tumor and
stromal cells promotes cancer progression. Hypoxia is one of the most common conditions …