Novel approaches for the design, delivery and administration of vaccine technologies

J Wallis, DP Shenton, RC Carlisle - Clinical & Experimental …, 2019 - academic.oup.com
It is easy to argue that vaccine development represents humankind's most important and
successful endeavour, such is the impact that vaccination has had on human morbidity and …

Towards tailored vaccine delivery: needs, challenges and perspectives

JP Amorij, GFA Kersten, V Saluja, WF Tonnis… - Journal of Controlled …, 2012 - Elsevier
The ideal vaccine is a simple and stable formulation which can be conveniently
administered and provides life-long immunity against a given pathogen. The development of …

[HTML][HTML] Novel approaches to vaccine delivery

DT O'Hagan, R Rappuoli - Pharmaceutical research, 2004 - Springer
Although the currently available vaccines represent an outstanding success story in modern
medicine and have had a dramatic effect on morbidity and mortality worldwide, it is clear that …

[HTML][HTML] Recent trends in vaccine delivery systems: a review

CH Saroja, PK Lakshmi… - International journal of …, 2011 - ncbi.nlm.nih.gov
Vaccines are the preparations given to patients to evoke immune responses leading to the
production of antibodies (humoral) or cell-mediated responses that will combat infectious …

New technologies for making vaccines

RW Ellis - Vaccine, 1999 - Elsevier
Technologies for making active vaccines fall into 3 general groups: live, subunit (killed or
inactivated) and genetic. Each of these groups is further divisible into multiple categories …

[HTML][HTML] Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities

M Ghattas, G Dwivedi, M Lavertu, MG Alameh - Vaccines, 2021 - mdpi.com
Vaccination is a key component of public health policy with demonstrated cost-effective
benefits in protecting both human and animal populations. Vaccines can be manufactured …

Vaccines: the fourth century

SA Plotkin - Clinical and Vaccine Immunology, 2009 - Am Soc Microbiol
Vaccine development, which began with Edward Jenner's observations in the late 18th
century, has entered its 4th century. From its beginnings, with the use of whole organisms …

[HTML][HTML] Vaccine development: From concept to early clinical testing

AL Cunningham, N Garçon, O Leo, LR Friedland… - Vaccine, 2016 - Elsevier
In the 21st century, an array of microbiological and molecular allow antigens for new
vaccines to be specifically identified, designed, produced and delivered with the aim of …

Old and new vaccine approaches

R Arnon, T Ben-Yedidia - International immunopharmacology, 2003 - Elsevier
The conventional, currently available vaccines, though quite successful, suffer from a few
shortcomings which hamper future vaccine development. We present herewith some of the …

Use of viral vectors for the development of vaccines

M Liniger, A Zuniga, HY Naim - Expert review of vaccines, 2007 - Taylor & Francis
The exceptional discoveries of antigen/gene delivery systems have allowed the
development of novel prophylactic and therapeutic vaccine candidates. This review …