The impact of metabolites derived from the gut microbiota on immune regulation and diseases

H Ohno - International Immunology, 2020 - academic.oup.com
Abstract The gut microbiota strongly impacts the physiology and pathology in the host. To
understand the complex interactions between host and gut microbiota, an 'integrated omics' …

Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis

J Wang, N Zhu, X Su, Y Gao, R Yang - Cells, 2023 - mdpi.com
The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

The gut microbiota: how does it influence the development and progression of liver diseases

P Kanmani, K Suganya, H Kim - Biomedicines, 2020 - mdpi.com
The gut–liver axis plays important roles in both the maintenance of a healthy liver and the
pathogenesis of liver diseases, where the gut microbiota acts as a major determinant of this …

[HTML][HTML] The gut microbiota at the service of immunometabolism

C Michaudel, H Sokol - Cell metabolism, 2020 - cell.com
The gut microbiota is implicated in immune system functions. Regulation of the metabolic
processes occurring in immune cells is crucial for the maintenance of homeostasis and …

Gut and obesity/metabolic disease: focus on microbiota metabolites

K Lin, L Zhu, L Yang - MedComm, 2022 - Wiley Online Library
Obesity is often associated with the risk of chronic inflammation and other metabolic
diseases, such as diabetes, cardiovascular disease, and cancer. The composition and …

A cross-talk between microbiota-derived short-chain fatty acids and the host mucosal immune system regulates intestinal homeostasis and inflammatory bowel …

P Gonçalves, JR Araújo… - Inflammatory bowel …, 2018 - academic.oup.com
Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential
for proper “education” of the immune system. Intestinal microbial communities are able to …

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism

SA Jasim, MJC Opulencia, AA Ramírez-Coronel… - International …, 2022 - Elsevier
The accumulating evidence revealed that microbiota plays a significant function in training,
function, and the induction of host immunity. Once this interaction (immune system …

[HTML][HTML] The Role of Gut Microbiota associated Metabolites in Digestive Disorders

N Li, C Zhao, P Zhang, S Wu, X Dou, S Xu… - Engineered …, 2024 - Elsevier
The gut has been a focal point in the research of digestive system disorders. The internal
microbiota generates metabolites that function as signaling molecules and substrates …

Microbial metabolites produced by the colonic microbiota as drivers for immunomodulation in the host

K Venema - 2013 - Wiley Online Library
The colonic microbiota ferments dietary substrates that are not digested in the upper GI tract,
such as complex carbohydrates. Fermentation of these leads to the production of short chain …

Role of intestinal microbiota and metabolites on gut homeostasis and human diseases

L Lin, J Zhang - BMC immunology, 2017 - Springer
Background A vast diversity of microbes colonizes in the human gastrointestinal tract,
referred to intestinal microbiota. Microbiota and products thereof are indispensable for …