Characterization of the humoral immune response to BNT162b2 in elderly residents of long-term care facilities five to seven months after vaccination

M Delbrück, S Hoehl, T Toptan, B Schenk, K Grikscheit… - medrxiv, 2021 - medrxiv.org
The elderly residing in long-term care facilities (LTCFs) are a group at high risk for COVID-
19. Hence, monitoring of the vaccine-based immunity has a pivotal role in identifying …

Reduced humoral response 3 months following BNT162b2 vaccination in SARS-CoV-2 uninfected residents of long-term care facilities

M Trigueros, E Pradenas, D Palacín… - Age and …, 2022 - academic.oup.com
Background SARS-CoV-2 vaccination is the most effective strategy to protect older residents
of long-term care facilities (LTCF) against severe COVID-19, but primary vaccine responses …

Antibody response 3 months after 2 doses of BNT162b2 mRNA COVID-19 vaccine in residents of long-term care facilities

R Causa, D Almagro-Nievas, M Rivera-Izquierdo… - Gerontology, 2022 - karger.com
Background: Older adults living in long-term care facilities (LTCFs) are at increased risk for
severe outcomes from COVID-19 and were identified as a priority group in COVID-19 …

Immunogenicity of the BNT162b2 mRNA COVID-19 vaccine in older residents of a long-term care facility: relation with age, frailty and prior infection status

P Seiffert, A Konka, J Kasperczyk, J Kawa, M Lejawa… - Biogerontology, 2022 - Springer
Clinical and biological assessment of the COVID-19 vaccine efficacy in the frail population is
of crucial importance. The study focuses on measuring the levels of anti-SARS-CoV-2 IgG …

[HTML][HTML] Weak humoral immune reactivity among residents of long-term care facilities following one dose of the BNT162b2 mRNA COVID-19 vaccine

MA Brockman, F Mwimanzi, Y Sang, K Ng, O Agafitei… - medRxiv, 2021 - ncbi.nlm.nih.gov
Background. Several Canadian provinces are extending the interval between COVID-19
vaccine doses to increase population vaccine coverage more rapidly. However …

BNT162b2 vaccination elicits strong serological immune responses against SARS-CoV-2 including variants of concern in elderly convalescents

B Jahrsdörfer, D Fabricius, J Scholz, C Ludwig… - Frontiers in …, 2021 - frontiersin.org
Elderly residents of long-term care facilities (LTCFs) have long been underrepresented in
studies on vaccine efficacy, particularly in light of currently emerging variants of concern …

B and T cell immune responses elicited by the BNT162b2 (Pfizer–BioNTech) COVID-19 vaccine in nursing home residents

I Torres, E Albert, E Giménez, MJ Alcaraz, P Botija… - medRxiv, 2021 - medrxiv.org
Objectives The immunogenicity of the BNT162b2 COVID-19 vaccine is understudied in
elderly people with comorbidities. We assessed SARS-CoV-2-S-targeted antibody and T cell …

Low but recoverable markers of humoral immune response to BNT162b2 in elderly LTCF residents five to seven months after two-dose vaccination

M Delbrück, S Hoehl, T Toptan, B Schenk… - Frontiers in …, 2022 - frontiersin.org
The immune response is known to wane after vaccination with BNT162b2, but the role of
age, morbidity and body composition is not well understood. We conducted a cross …

Sero-survey on long-term care facility residents reveals increased risk of sub-optimal antibody response to BNT162b2: implications for breakthrough prevention

B Caimi, M Franzetti, R Velleca, A Lai, A Gatti, PL Rossi… - BMC geriatrics, 2022 - Springer
Background The impact of coronavirus disease 2019 (COVID-19) caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) on residents of long-term care facilities …

Humoral and cellular responses to COVID-19 vaccination indicate the need for post-vaccination testing in frail population

W Witkowski, S Gerlo, E De Smet, M Wejda, D Acar… - Vaccines, 2022 - mdpi.com
Despite the high efficacy of the BNT162b2 vaccine in the general population, data on its
immunogenicity among frail elderly individuals are limited. Recently, levels of anti-SARS …