Absent reflex tachycardia with captopril therapy suggests blunting of circulatory reflexes,
perhaps contributing to antihypertensive efficacy, and angiotensin converting enzyme …

Captopril lowers blood pressure without increasing heart rate and plasma norepinephrine,
which suggests that this drug may potentiate arterial baroreflexes. In eight subjects with …

The effects of acute administration of captopril on heart rate, blood pressure and
physiological responses to head-up tilt, hand-grip, exercise and Valsalva manoeuvre were …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

Twenty severely hypertensive subjects who did not achieve blood pressure control with
combination therapy with a vasodilator, a beta-adrenergic blocking agent and a diuretic …

Eight diabetic subjects with moderately elevated blood pressure (BP)(systolic (SBP) greater
than 140 and/or diastolic (DBP) greater than 90 mmHg) were studied. Each had evidence of …

Previous studies from our laboratory have shown that chronic intracerebroventricular
administration of captopril attenuates the development of hypertension in the spontaneously …

Many vasodilators have been tried as antianginal agents, but the reflex increase in
sympathetic tone produced by these drugs necessitate their use with caution in patients with …

In 16 male patients with heart failure (NYHA II-III), the influence of a single dose of 25 mg
captopril on the carotid sinus baroreceptor reflex was examined. Blood presure fell …

The effect on arterial pressure of incremental doses of norepinephrine (2 to 10 µg/min) and
angiotensin II (50 to 800 ng/min) administered over 10 min periods was studied in sodium …