Spontaneously hypertensive rats (SHR) demonstrate elevated blood pressure, cardiac
hypertrophy, glucose intolerance, and insulin resistance compared with age-matched Wistar …

The acute effects of captopril on blood pressure, renin, angiotensin, bra‐dykinin and
catecholamines were examined in patients with essential (n= 10, Group 1), accelerated (n …

The effect on blood pressure and heart rate, following administration of the same
intracerebroventricular (ivt) and intravenous (iv) doses of captopril, was compared in freely …

Nine patients with essential hypertension treated with bendroflumethiazide were given
captopril 25 mg orally on three occasions to study the pharmacokinetics and blood pressure …

Acute and chronic antihypertenslve effects of the angiotensin conferring enzyme inhibitor,
captoprii (SQ 14,225), was assessed in 29 consecutirely-studled patients with …

To compare the antihypertensive and Immoral effects of the angiotensin-converting enzyme
inhibitors captopril and enalapril, 20 patients with essential hypertension, not receiving …

Baroreflex sensitization and direct sympatholytic effects have been suggested as
contributing mechanisms to the effects of dihydropyridine calcium channel blockers in …

1 The long‐term effect of the converting‐enzyme inhibitor captopril was investigated in 76
patients with various forms of severe hypertension, most cases being resistant to a …

A triphasic pattern of blood pressure response was observed in 13 of 26 patients treated
with captopril. Pressure fell after the first dose in all but 3 patients, reaching a minimum by 90 …

Two groups, each with nine essential hypertensive patients, were maintained on 10 mmol
sodium daily over 14-17 days and treated in this sequence:(1) placebo;(2) captopril (25 or …