To determine whether prostaglandins contribute to the depressor response to the converting
enzyme inhibitor, captopril, we measured the plasma prostaglandin levels by …

The influence of captopril (SQ 14225) on the vascular and norepinephrine-releasing
responses to nerve stimulation (2, 5 and 10 Hz) was assessed in isolated blood-free …

1. Captopril (25 mg) reduced plasma angiotensin II (ANG II) by 53%(P< 0· 001) and mean
brachial artery pressure (MBAP) by 18· 7 mmHg (P< 0· 001) within 75 min in 26 hypertensive …

Earlier studies have shown that cardiovascular autonomic regulation is impaired in
untreated or poorly controlled systemic hypertension. The purpose of this double-blind …

Ten patients with severe hypertension and unsatisfactory blood pressure control during
combined therapy with β‐adrenergic blocking drugs, diuretics, and vasodilators were treated …

The effect of captopril 25 to 50 mg twice daily on 24 h blood pressures was compared with
placebo in 14 patients with essential hypertension. Captopril was started in a dose of 25 mg …

Prazosin, a peripherally active alpha‐adrenoceptor antagonist, and clonidine, a centrally
active alpha‐adrenoceptor agonist, both reduce blood pressure but with different alterations …

The studies were designed to explore the effect of the converting enzyme inhibitor captopril
on the activity of the sympathetic nervous system during basal conditions and following …

The acute hypotensive effect of captopril 25 mg was investigated in 26 hypertensive patients
(11 with essential and 15 with renal arterial disease). Intra-arterial blood pressure was …

The control of heart rate by the arterial baroreceptors and the evidence that these reflexes
are impaired in people with raised arterial pressure are reviewed. The results with the …