Background Symptomatic malaria cases reflect only a small proportion of all Plasmodium
spp infections. Many infected individuals are asymptomatic, and persistent asymptomatic …

Achieving malaria elimination requires a better understanding of the transmissibility of
human infections in different transmission settings. This study aimed to characterize the …

Introduction In order to improve our understanding of the fundamental limits of core
interventions and guide efforts based on prioritization and identification of effective/novel …

Background Recent data indicate that non-Plasmodium falciparum species may be more
prevalent than thought in sub-Saharan Africa. Although Plasmodium malariae, Plasmodium …

Background A substantial proportion of Plasmodium species infections are asymptomatic
with densities too low to be detectable with standard diagnostic techniques. The importance …

A detailed understanding of the human infectious reservoir is essential for improving malaria
transmission-reducing interventions. Here we report a multi-regional assessment of …

Background As indicators of burden of malaria have substantially decreased in The Gambia,
reaching a pre-elimination status may be attainable. Achieving this goal requires in-depth …

After 2 decades of using insecticide-treated nets (ITNs) and improved case management,
malaria burden in the historically-holoendemic Kilombero valley in Tanzania has …

Background. Variation in the risk of malaria within populations is a frequently described but
poorly understood phenomenon. This heterogeneity creates opportunities for targeted …

The intensification of control interventions has led to marked reductions in malaria burden in
some settings, but not others. To provide a comprehensive description of malaria …