[HTML][HTML] Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication

B Ramnani, S Powell, AG Shetty, P Manivannan… - Viruses, 2023 - mdpi.com
Virus infection activates integrated stress response (ISR) and stress granule (SG) formation
and viruses counteract by interfering with SG assembly, suggesting an important role in …

[HTML][HTML] Effect of the viral hemorrhagic septicemia virus nonvirion protein on translation via PERK-eIF2α pathway

SP Kesterson, J Ringiesn, VN Vakharia, BS Shepherd… - Viruses, 2020 - mdpi.com
Viral hemorrhagic septicemia virus (VHSV) is one of the most deadly infectious fish
pathogens, posing a serious threat to the aquaculture industry and freshwater ecosystems …

Roles of stress-activated protein kinases in the replication of Singapore grouper iridovirus and regulation of the inflammatory responses in grouper cells

X Huang, Y Huang, Z OuYang, J Cai… - Journal of general …, 2011 - microbiologyresearch.org
Stress-activated protein kinases (SAPKs), including p38 mitogen-activated protein kinase
(p38 MAPK) and c-Jun N-terminal kinase (JNK), are usually activated in response to …

[HTML][HTML] Critical Roles of G3BP1 in Red-Spotted Grouper Nervous Necrosis Virus-Induced Stress Granule Formation and Viral Replication in Orange-Spotted Grouper …

M Sun, S Wu, S Kang, J Liao, L Zhang, Z Xu… - Frontiers in …, 2022 - frontiersin.org
Viral infection causes changes in the internal environment of host cells, and a series of
stress responses are generated to respond to these changes and help the cell survive …

[HTML][HTML] The regulation of integrated stress response signaling pathway on viral infection and viral antagonism

Y Wu, Z Zhang, Y Li, Y Li - Frontiers in microbiology, 2022 - frontiersin.org
The integrated stress response (ISR) is an adaptational signaling pathway induced in
response to different stimuli, such as accumulation of unfolded and misfolded proteins …

Quantitative proteomic analysis reveals unfolded-protein response involved in severe fever with thrombocytopenia syndrome virus infection

LK Zhang, B Wang, Q Xin, W Shang, S Shen… - Journal of …, 2019 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging, highly pathogenic,
infectious disease caused by infection with a newly discovered tick-borne phlebovirus, SFTS …

Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses

CS Ng, M Jogi, JS Yoo, K Onomoto, S Koike… - Journal of …, 2013 - Am Soc Microbiol
In response to stress, cells induce ribonucleoprotein aggregates, termed stress granules
(SGs). SGs are transient loci containing translation-stalled mRNA, which is eventually …

Stress granules in the viral replication cycle

H Montero, V Trujillo-Alonso - Viruses, 2011 - mdpi.com
As intracellular parasites, viruses require a host cell in order to replicate. However, they face
a series of cellular responses against infection. One of these responses is the activation of …

[HTML][HTML] Mumps virus induces protein-kinase-R-dependent stress granules, partly suppressing type III interferon production

S Hashimoto, S Yamamoto, N Ogasawara, T Sato… - PLoS …, 2016 - journals.plos.org
Stress granules (SGs) are cytoplasmic granular aggregations that are induced by cellular
stress, including viral infection. SGs have opposing antiviral and proviral roles, which …

[HTML][HTML] African swine fever virus pS273R antagonizes stress granule formation by cleaving the nucleating protein G3BP1 to facilitate viral replication

T Li, X Li, X Wang, X Chen, G Zhao, C Liu… - Journal of Biological …, 2023 - ASBMB
Cytoplasmic stress granules (SGs) are generally triggered by stress-induced translation
arrest for storing mRNAs. Recently, it has been shown that SGs are regulated by different …