[HTML][HTML] Nonstructural protein of severe fever with thrombocytopenia syndrome phlebovirus inhibits TBK1 to evade interferon-mediated response

JK Lee, OS Shin - Journal of microbiology and biotechnology, 2021 - ncbi.nlm.nih.gov
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging phlebovirus of
the Phenuiviridae family that has been circulating in the following Asian countries: Vietnam …

[HTML][HTML] Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity

K Onomoto, M Jogi, JS Yoo, R Narita, S Morimoto… - 2012 - journals.plos.org
Retinoic acid inducible gene I (RIG-I)-like receptors (RLRs) function as cytoplasmic sensors
for viral RNA to initiate antiviral responses including type I interferon (IFN) production. It has …

Proteomic profiling of protease-primed virus-permissive Caco-2 Cells Display Abortive-Interferon Pathway and Deregulated thromboinflammatory SERPINS

M Sharma, NK Panda - 2020 - preprints.org
Emerging paradigms in interferon (IFN) biology suggest a dynamic INF induced interactome
that extends through broader Interferon Stimulated Gene (ISG)-induction, which implicates …

African Swine Fever Virus Host–Pathogen Interactions

CL Netherton, GL Shimmon, JYK Hui, S Connell… - Virus Infected Cells, 2023 - Springer
African swine fever virus is a complex double-stranded DNA virus that exhibits tropism for
cells of the mononuclear phagocytic system. Virus replication is a multi-step process that …

Herpes simplex virus 2 virion host shutoff endoribonuclease activity is required to disrupt stress granule formation

RL Finnen, M Zhu, J Li, D Romo, BW Banfield - Journal of virology, 2016 - Am Soc Microbiol
We previously established that cells infected with herpes simplex virus 2 (HSV-2) are
disrupted in their ability to form stress granules (SGs) in response to oxidative stress and that …

Spring Viremia of Carp Virus N Protein Negatively Regulates IFN Induction through Autophagy-Lysosome–Dependent Degradation of STING

X Wang, ZC Li, C Zhang, JY Jiang, K Han… - The Journal of …, 2023 - journals.aai.org
Fish possess a powerful IFN system to defend against aquatic virus infections. Nevertheless,
spring viremia of carp virus (SVCV) causes large-scale mortality in common carp and …

Puumala and Andes orthohantaviruses cause transient protein kinase R-dependent formation of stress granules

W Christ, J Tynell, J Klingström - Journal of Virology, 2020 - Am Soc Microbiol
Virus infection frequently triggers host cell stress signaling resulting in translational arrest; as
a consequence, many viruses employ means to modulate the host stress response …

Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis

X Huang, Y Huang, Y Yang, S Wei, Q Qin - Fish & Shellfish Immunology, 2014 - Elsevier
Signal transducer and activator of transcription 3 (STAT3) is an important transcription factor
which plays crucial roles in immune regulation, inflammation, cell proliferation …

Two conserved amino acids within the NSs of severe fever with thrombocytopenia syndrome phlebovirus are essential for anti-interferon activity

M Moriyama, M Igarashi, T Koshiba, T Irie… - Journal of …, 2018 - Am Soc Microbiol
The nonstructural protein (NSs) of severe fever with thrombocytopenia syndrome
phlebovirus (SFTSV) sequesters TANK-binding kinase 1 (TBK1) into NSs-induced …

p38 and STAT3 activation by vGPCR in KSHV-infected cells

M Liu, S Guo - Virus Adaptation and Treatment, 2010 - Taylor & Francis
The molecular mechanism whereby viral G protein-coupled receptor (vGPCR) signaling
regulates vascular endothelial growth factor (VEGF) expression in Kaposi sarcoma (KS) …