VEGF receptor signaling and endothelial function

S Kliche, J Waltenberger - IUBMB life, 2001 - Wiley Online Library
Angiogenesis, the formation of new blood vessels from preexisting ones, is a central process
during normal development and during pathological repair. Vascular endothelial growth …

Roles of VEGF-A signalling in development, regeneration, and tumours

K Matsumoto, M Ema - The journal of biochemistry, 2014 - academic.oup.com
Angiogenesis, the formation of new networks of blood vessels, has essential roles in
embryonic development, organ homeostasis and disease progression. Several signalling …

Signaling pathways induced by vascular endothelial growth factor

B Larrivee, A Karsan - International journal of …, 2000 - spandidos-publications.com
Vasculogenesis and angiogenesis are the mechanisms responsible for the development of
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …

Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis

M Shibuya - BMB Reports, 2006 - koreascience.kr
Vascular endothelial growth factor (VEGF)-A, a major regulator for angiogenesis, binds and
activates two tyrosine kinase receptors, VEGFR1 (Flt-1) and VEGFR2 (KDR/Flk-1). These …

[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis

CS Melincovici, AB Boşca, S Şuşman… - Rom J Morphol …, 2018 - rjme.ro
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis

CS Abhinand, R Raju, SJ Soumya, PS Arya… - Journal of cell …, 2016 - Springer
Vascular endothelial growth factor-A (VEGF-A) is essential for endothelial cell functions
associated with angiogenesis. Signal transduction networks initiated by VEGFA/VEGFR2 …

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

M Shibuya, L Claesson-Welsh - Experimental cell research, 2006 - Elsevier
The VEGF/VPF (vascular endothelial growth factor/vascular permeability factor) ligands and
receptors are crucial regulators of vasculogenesis, angiogenesis, lymphangiogenesis and …

Functions of the VEGF/VEGF receptor system in the vascular system

G Breier - Seminars in thrombosis and hemostasis, 2000 - thieme-connect.com
The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central
regulatory role in physiological and pathological angiogenesis. During embryogenesis, the …

VEGFs, receptors and angiogenesis

T Veikkola, K Alitalo - Seminars in cancer biology, 1999 - Elsevier
Angiogenesis, the formation of new blood vessels from pre–-existing ones, is central for both
normal development and homeostasis as well as in certain pathological conditions. The …

Mechanisms and regulation of endothelial VEGF receptor signalling

M Simons, E Gordon, L Claesson-Welsh - Nature reviews Molecular …, 2016 - nature.com
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …