Hormonal control of germ cell development and spermatogenesis
PJ O'Shaughnessy - Seminars in cell & developmental biology, 2014 - Elsevier
Spermatogenesis is completely dependent on the pituitary hormone follicle-stimulating
hormone (FSH) and androgens locally produced in response to luteinising hormone (LH) …
hormone (FSH) and androgens locally produced in response to luteinising hormone (LH) …
The endocrine regulation of spermatogenesis: independent roles for testosterone and FSH
RI McLachlan, NG Wreford, L O'donnell… - Journal of …, 1996 - joe.bioscientifica.com
Introduction The adult testis has two important roles, namely the production of spermatozoa
(fertility) and the secretion of testosterone which is needed for the expression of secondary …
(fertility) and the secretion of testosterone which is needed for the expression of secondary …
Hormonal regulation of male germ cell development.
SM Ruwanpura, RI McLachlan… - The Journal of …, 2010 - europepmc.org
Over the past five decades, intense research using various animal models, innovative
technologies notably genetically modified mice and wider use of stereological methods …
technologies notably genetically modified mice and wider use of stereological methods …
[PDF][PDF] Hormonal regulation of spermatogenesis in primates and man: insights for development of the male hormonal contraceptive
RI McLachlan, L O'DONNELL, SJ Meachem… - Journal of …, 2002 - academia.edu
A better understanding of the hormonal regulation of spermatogenesis may provide new
avenues for management of human infertility, and development of safe and reversible …
avenues for management of human infertility, and development of safe and reversible …
Spermatogenesis: its regulation by testosterone and FSH
BR Zirkin - Seminars in cell & developmental biology, 1998 - Elsevier
It has been clear for decades that testosterone is a necessary prerequisite for the
maintenance of established spermatogenesis in the adult testes, and for the restoration of …
maintenance of established spermatogenesis in the adult testes, and for the restoration of …
[HTML][HTML] Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors
PJ O'shaughnessy, A Monteiro… - Reproduction …, 2010 - ncbi.nlm.nih.gov
FSH and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the
Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen …
Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen …
Role of follicle-stimulating hormone in spermatogenesis
OO Oduwole, H Peltoketo, IT Huhtaniemi - Frontiers in endocrinology, 2018 - frontiersin.org
Spermatogenesis is a concerted sequence of events during maturation of spermatogonia
into spermatozoa. The process involves differential gene-expression and cell-cell interplay …
into spermatozoa. The process involves differential gene-expression and cell-cell interplay …
[PDF][PDF] Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys, and man
RI McLachlan, L O'Donnell, SJ Meachem… - Recent progress in …, 2002 - researchgate.net
ABSTRACT A detailed understanding of the hormonal regulation of spermatogenesis is
required for the informed assessment and management of male fertility and, conversely, for …
required for the informed assessment and management of male fertility and, conversely, for …
Sertoli and Germ Cell Development in Hypogonadal (hpg) Mice Expressing Transgenic Follicle-Stimulating Hormone Alone or in Combination with Testosterone
M Haywood, J Spaliviero, M Jimemez, NJC King… - …, 2003 - academic.oup.com
We recently created a novel transgenic (tg) model to examine the specific gonadal actions of
FSH, distinct from LH effects, by expressing tg-FSH in gonadotropin-deficient hypogonadal …
FSH, distinct from LH effects, by expressing tg-FSH in gonadotropin-deficient hypogonadal …
Human Spermatogenesis in Vitro: Respective Effects of Follicle-Stimulating Hormone and Testosterone on Meiosis, Spermiogenesis, and Sertoli Cell Apoptosis
J Tesarik, M Guido, C Mendoza… - The Journal of Clinical …, 1998 - academic.oup.com
In spite of the availability of abundant data about in vitro spermatogenesis in laboratory
animals, studies on human in vitro spermatogenesis are scarce. This study employed a …
animals, studies on human in vitro spermatogenesis are scarce. This study employed a …